The Scotsman

NEW VACCINE HOPE,

- By HANNAH BROWN hannah.brown@jpimedia.co.uk

The chance soft he University of Oxford' s Covid-19 vaccine being rolled out by the end of this year are" pretty high", according to the lead researcher of the jab.

Sarah Gilbert, professor of vaccinolog­y at the university, emphasised that multiple vaccines – made using different technologi­es – will be needed to tackle the pandemic.

The jab from Oxford and pharmaceut­ical giant AstraZenec­a is yet to be approved for use in the UK, with the Medicine sand Healthcare products Regulatory Agency (MHR A) still reviewing trial data.

When asked about the chances of receiving the jab by the end of the year, Prof Gilbert told the BBC'S Andrew Marr Show :" It depends on the age group you're in and the J CV I( Joint Committee on Vaccinatio­n and Immunisati­on) prioritisa­tions. "I think the chances are pretty high. But we do need multiple vaccines, all countries need multiple vaccines, the world needs mul tip lev accines and we need vaccines made using different technologi­es, if that's possible ." She said this was due to companies potentiall­y encounteri­ng problems with the sup - ply of raw materials as doses are produced, which could slow down vaccine rollout if other jabs are not available. "So having multiple shots on goal, multiple irons in the fire, is what we really need ," she added. Astrazenec­a has joined a trial exploring whether a combinatio­n of its vaccine candidate and the Russian Sputnik V jab can offer improved protection from the virus.

Sputnik V, currently being made available to Russians in high-risk groups, was given regulatory approval by the Russian government in early August amid criticism after only being tested on several dozen people.

Prof Gilbert said there was a "possibilit­y" that the Oxford/ Astrazenec­a jab could give better protection if combined with other candidates, but added there would be "much more considerat­ion" before it is used on a larger scale.

"Well, this is just going to be a small trial to star t with, to look at what can be achieved by using those two vaccines together," she told the Andrew M arr Show ." There'll obviously be much more considerat­ion given to whether it should be used on a wide scale. Data indicates the Oxford/ AstraZenec­a vaccine has 62 percent efficacy when one full dose is given followed by another full dose, but when people were given a half dose followed by a full dose at least a month later, its efficacy rose to 90 p er cent. The combined analysis from both do sing regimes resulted in an average efficacy of 70 percent. Meanwhile, the vaccine by Pfize rand BioNTech, which is currently being rolled out across the UK, has been shown in studies to be 95 per cent effective and works in all age groups. The UK has secured 100 million doses of the Oxford/astraZenec­a jab and 40 million of the Pfizer/biontech vaccine. On concerns over the efficacy of the Oxford/astrazenec­a jab, Prof Gilbert said: "What's important is vaccinatin­g population, not vaccinatin­g people and thinking about efficacy on an individual level."

 ??  ?? 0 It is hoped that the Oxford vaccine could be rolled out by the end of the year
0 It is hoped that the Oxford vaccine could be rolled out by the end of the year

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