The Scotsman

PM hails ‘ fantastic news’ as third vaccine approved for use in UK

- By ANGUS HOWARTH newsdeskts@ scotsman. com

Prime Minister Boris Johnson has said it is "excellent news" that a third coronaviru­s vaccine has been approved for use in the UK.

The jab, from US biotech firm Moderna, has been given the green light by the Medicines and Healthcare products Regulatory Agency ( MHRA), joining the vaccines from Pfize r-Bi on tec hand OxfordAstr­azeneca.

The Moderna jab has been shown to be 94 percent effective against C ovid -19 and should be available in the UK from the spring.

The UK Government has increased its order of the vaccine to 17 million dose s–enough to vaccinate 8.5 million people – with batches expected to be released in phases.

Mr Johnson tweeted: "Excellent news the @ Mhragovuk has approved the use of the @ moderna_ tx vaccine.

"Our national vaccine effort is accelerati­ng to vaccinate priority groups with our existing two vaccines, and the Moderna doses will add to that when they become available in spring."

Health Secretary Matt Hancock tweeted: "This is fantastic news and another weapon in our arsenal to tame this awful disease."

Nearly 1.5 million people in the UK have already been vaccinated with thePfize r-Bi onTe cha nd Oxford University­Astrazenec­a vaccines, with the Government aiming to jab 15 million of those most at risk by mid- February.

The news comes as London mayor Sadiq Khan declared a "major incident" as the spread of coronaviru­s threatens to "overwhelm" the capital's hospitals.

City Hall said Covid- 19 cases in London had exceeded 1,000 per 100,000, while there are 35 per cent more people in hospital with the virus than in the peak of the pandemic in April.

A "major incident" means the" severity of the con sequences" associated with it are "likely to constrain or complicate the ability of responders to resource and manage the incident".

Professor Kevin Fenton, Public Health England's regional director for London, said: "This is the biggest threat our city has faced in this pandemic to date.

"The emergence of the new variant means we are setting record case rates at almost double the national average, with at least one in 30 people ( in London) now thought to be carrying the virus.

"Our NHS services are under immense pressure and currently another 800 people are being admitted to our hospitals every day."

Scientists advising the Government believe the lockdown may lead to a plateau of cases of coronaviru­s across the UK rather than the dramatic cut seen in the March and April lockdown.

They estimate there are more than 100,000 new infections a day and possibly higher than 150,000.

They believe this estimate puts the current number of daily cases at a higher level than during the first wave of the pandemic.

With the current lockdown and vaccine roll- out, deaths from coronaviru­s are expected to start dropping in February, while hospital admissions should drop after that.

Corona virus cases are expected to drop in the spring due to vaccinatio­n plus the fact people spend more time outdoors, making it harder for the virus to spread.

Elsewhere, research published yesterday suggests the Covid- 19 vaccine from Pfizer and Biontech appears to protect against a mutation in two coronaviru­s variants that are causing spread across the UK.

The pharmaceut­ical firm and researcher­s from the University of Texas medical branch carried out lab tests on the strains, one of which was found in the UK while the other originated in South Africa.

Both variants contain mutations including N501Y, an alteration in the spike protein of the virus, which is a target for vaccines.

In the new study, which has not been peer- reviewed, people given the Pfizer jab had neutralisi­ng levels of antibodies which appeared to work against N501Y in the new strains.

However, one of the mutations in the South Africa variant, named E484K, has not yet been studied and is still causing concern for experts. While scientists at the top of Government increasing­ly believe the UK variant can be tackled with existing vaccines, there is concern that the South African variant has the potential to make them less effective, although studies are still continuing.

In future years, it is thought that Covid- 19 vaccines will need to be tweaked annually, much in the same way the winter flu jab is, to ensure they remain effective in fighting off newly evolving strains of the virus.

It comes as the reproducti­ve rate – the R number – of the virus is thought to be between one and 1.4. The R refers to the number of people an infected person will pass the virus onto.

Meanwhile papers released by the government from the scientific Pandemic influenza group on Behaviours ( SPI- B), which advises ministers, suggests communicat­ion campaigns will be needed to ensure those who are vaccinated continue to adhere to lockdown rules.

It said there was some evidence that, "in the absence of any mitigation policies, some of those who have been vaccinated will show a reduction in personal protective behaviours" such as mask- wearing and social distancing.

It is not yet known whether vaccinatio­n can prevent people passing the virus onto other people.

 ??  ?? 0 The UK Government has increased its order of the Moderna vaccine to 17 million doses
0 The UK Government has increased its order of the Moderna vaccine to 17 million doses
 ??  ?? 0 Boris Johnson: ‘ National vaccine effort is accelerati­ng’
0 Boris Johnson: ‘ National vaccine effort is accelerati­ng’

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