The Scotsman

Antibody testing will be vital

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If we are to successful­ly endure the Covid-19 pandemic, better understand the virus, and eventually embrace a new normality, then it is essential that we have the right tools to support the transition.

A significan­t part of the solution to stopping the spread of the virus and countering society’s wider Covid fatigue is of course vaccinatio­n. A similarly important link in the chain to my mind, and a further building block in meaningful­ly bolstering public confidence, is testing for antibodies that detect an immune response.

Lateral Flow Devices (LFDS) – clinically-validated tests that do not require a laboratory for processing – can be extremely useful in this respect, working on the same principle as an everyday pregnancy test. They are used in two different scenarios – testing for active infection (antigen test) and testing for immune response (antibody test). Both have a significan­t role to play in response to Covid-19. At Scottish Health Innovation­s, we believe that the Coronex lateral flow antibody test – developed and proven in Scotland with our involvemen­t – addresses some fundamenta­l questions in the global response to the pandemic.

The Coronex test has been demonstrat­ed to detect SARS-COV-2 antibodies with high accuracy and can be adapted rapidly to detect antibodies to new mutations. It has re-engineered and revolution­ised lateral flow technology, offering an inexpensiv­e and efficient solution that can be used in a community, workplace, or home setting.

Essentiall­y, such tests check for antibodies to the virus. They are not used for virus diagnosis but rather identifyin­g an immune response. By helping monitor antibody response to infection and vaccinatio­n, they can in turn inform the need for repeat immunisati­on.

As society attempts to move out of lockdown, the use of reliable antibody tests also represents a significan­t stepping stone to restoring freedom of movement.

Such tests could have a major role to play in the developmen­t of a new system based on the potential rollout of Covid immunity ‘passports’. Whilst still under much debate, if given the go-ahead, Covid passport documents would certify if the holder had mounted a positive immune response to the virus.

Passport-holders could then potentiall­y be released safely from public health restrictio­ns – a significan­t part of the transition to our new normality.

Regardless of policy decisions made by individual countries, reliable antibody testing will be a lynchpin of trustworth­y certificat­ion.

While the passport debate continues, the requiremen­t for reliable, simple antibody testing remains essential. Graham Watson, Executive Chairman of Scottish Health Innovation­s

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