The Scotsman

People with severe cataracts have higher risk of premature death, study suggests

- By ELLA PICKOVER newsdeskts@scotsman.com

People who have cataract surgery are more likely to die prematurel­y, a new study suggests.

They are also more likely to die from issues of the heart and circulator­y system, researcher­s found.

Previous studies have shown conflictin­g evidence as to whether people who undergo cataract surgery have a higher risk of "all cause mortality", according to experts from China.

So they set out to assess whether those who undergo such operations have a higher risk of different causes of death - such as death from cancer, Alzheimer's and kidney disease.

Cataracts occur when cloudy patches develop on the lens of the eye, over time these can become bigger and cause a loss of vision and even blindness.

Surgery involves replacing the cloudy lens inside with an artificial one.

Hundreds of thousands of cataract operations are conducted every year in the UK.

The new study, published in the British Journal of Ophthalmol­ogy, examined data on almost 15,000 people aged 40 and over who took part in the US National Health and Nutrition Examinatio­n Survey between 1999 and 2008.

During an average followup period of 10.8 years, almost 4,000 participan­ts died.

And 2,000 had received cataract surgery.

The researcher­s found that those who had cataract surgery were significan­tly more likely to have died during the follow-up compared to those who did not – 53 per cent of those who had the operation had died, compared to 15 per cent of those who did not.

But the overall picture masked a slightly complex situation when researcher­s examined different types of death.

After adjusting for various factors, they found that those who had cataract surgery had a 36 per cent increased risk of dying from vascular disease – which includes issues surroundin­g the heart and circulator­y system.

But there was no statistica­lly increased risk of death from cancer, accident, Alzheimer's disease, respirator­y disease or renal disease.

They called for further studies to examine the mechanism behind the findings.

"The current study found a positive associatio­n between self-reported cataract surgery and all-cause mortality," the authors wrote.

"In addition, we found that self-reported cataract surgery increases the risks of vascular mortality by 36 per cent after multiple adjustment­s.

"More studies are needed to confirm these associatio­ns and to further investigat­e the mechanisms behind these associatio­ns."

Earlier this month it emerged that scientists have developed a “pellet” implant that is injected into the eye to prevent cataracts forming and could reverse the growth of existing cataracts without surgery.

The implant, thought to work by lowering calcium levels in the eye, is being tested in the first clinical trial.

The implant is loaded with antioxidan­ts and injected into the vitreous — the gel-like fluid between the lens and retina (the light-sensitive area in the eye).

The implant slowly releases its contents into the vitreous, which carries them to the lens where it acts on the cataract.

 ?? ?? ↑ The researcher­s found that those who had cataract surgery were significan­tly more likely to die prematurel­y compared to those who did not
↑ The researcher­s found that those who had cataract surgery were significan­tly more likely to die prematurel­y compared to those who did not

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