The Scottish Mail on Sunday

At last... the no side effect cancer drug

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A BREAKTHROU­GH drug that mimics human immune cells is boosting survival chances of patients with incurable bowel cancer.

Specialist are hailing it as the first life-extending cancer drug without significan­t side effects. The new drug may mean that those with advanced disease no longer have to make the ‘quantity versus quality’ trade-off – either having gruelling chemothera­py in the hope of extending life, or concentrat­ing on best enjoying their last remaining days.

Normally patients lose weight, suffer fatigue, nausea, anaemia, lack of energy and suffer pain as a result of cancer treatment.

But Xilonix leaves patients feeling ‘unbelievab­ly well’, say experts.

The drug is a synthetic version of a human immune system cell known as an antibody that is naturally present in 20 per cent of the population and gives a degree of protection against bowel cancer.

Because the drug targets cancer cells rather than indiscrimi­nately attacking the rest of the body, it causes far fewer side effects.

Results from a British trial of 309 patients showed that Xilonix arrested the growth of tumours and those on it experience­d fewer symptoms. The trial also indicated that the so-called monoclonal antibody treatment would help some patients live longer.

Oncologist Tamas Hickish, from Bournemout­h Hospital, who led the trial, said: ‘I have never come across a cancer drug for advanced cancer that has almost zero side effects.’ And Dr Mark Sanders, an oncologist at The Christie hospital in Manchester, explained: ‘This drug latches on to the cancer and doesn’t affect the rest of the body.’ Ray Pollicott, 74, tried the experiment­al new drug after being told in 2015 that his cancer had spread so far he probably had only a few months to live. He said: ‘I am amazed at how well I’ve felt. I’ve been on five-mile walks and at times was almost able to forget I had cancer.’

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