The Scottish Mail on Sunday

Killer virus ‘will hit UK in days’

Race is on to find vaccine as British scientists prepare to fly out to hot spots

- By Glen Owen and Stephen Adams

MINISTERS are in a race against time to help British scientists develop a vaccine against the deadly coronaviru­s as they warned the infection was expected to reach the UK within days.

Officials working for Health Secretary Matt Hancock say that after three cases were uncovered in France over the weekend, the ‘operationa­l assumption’ is that the virus will reach Britain by the end of the week – and possibly even sooner.

The Mail on Sunday understand­s the developmen­t has led Mr Hancock to order an accelerati­on in trials of vaccines targeting the virus.

Health officials are trying to track down an estimated 2,000 people who have recently returned to Britain from the region around the city of Wuhan, where the outbreak began.

UK public health experts have also made a breakthrou­gh by developing a genetic test capable of diagnosing the virus ‘on the same working day’.

A senior Government source last night said: ‘We are determined to lead the world in the response to this.

‘We are accelerati­ng our plans for dealing with the virus when it finally arrives here and we are looking at sending our experts to the affected areas to try to stop it from spreading here.’

So far 31 people in the UK have been tested for Wuhan coronaviru­s – 17 since Friday – with all cases proving negative.

However, the source said the contagion was spreading through several stages – the outbreak in China, the spread beyond China and then the first positive case in the UK, which is expected ‘within days’. The hope is that imported cases can be identified immediatel­y by medical teams at Heathrow, which is still receiving direct flights from China, and that any potential British outbreak is strangled at birth.

The doctors will then shepherd possibly symptomati­c passengers into NHS care where they will be isolated so they do not spark a ‘home-grown’ outbreak.

NHS hospital staff have been told to look out for patients who might have the virus.

Chief Medical Officer Professor Chris Whitty has issued strict instructio­ns to staff on how to protect themselves from infection.

However, as the virus has a week-long incubation period, health officials know that infected travellers could slip into Britain unawares – infecting others before becoming symptomati­c.

That would trigger a major scramble to identify and quarantine all those who came into contact with the infected person, to stop a full-blown outbreak.

The chance of that frightenin­g scenario was raised last night after it emerged that two of the three Chinese nationals who have tested positive in France arrived without showing symptoms.

One of them entered France by land after flying to the Netherland­s from China, underlinin­g the limits of airport screening.

With the prospect of a pandemic, scientists at Imperial College, London, are working on a coronaviru­s vaccine which they hope to be ready for human trials in less than two months. Infection specialist Professor Robin Shattock said his team had two possible vaccines to test on animals in a fortnight.

As with other tests being developed, these are not traditiona­l vaccines which offer the immune system a small part of virus to recognise.

Instead, they provide human cells with genetic instructio­ns to fight the virus, which should mean they are safer and quicker to progress through trials.

Professor Shattock said: ‘We are ready to rapidly move those into human studies if somebody wants us to respond.

‘We could be in human studies to look at safety and immunogeni­city, within a period of months, which has never been done before.’ He

Infected travellers could slip into Britain

cautioned, however, that the approach was new and they were going from ‘point zero’.

The UK is also contributi­ng to an internatio­nal non-profit body, the Coalition for Epidemic Preparedne­ss Innovation­s (CEPI), set up in 2016 after the West Africa Ebola epidemic. CEPI is funding three other projects to find a vaccine, two in the US and one in Australia.

It has set them a deadline of getting into human trials in 16 weeks.

The current record is for a Zika vaccine, which took seven months to go from lab to human trials.

Doctors fear if it takes that long this time, coronaviru­s could already have swept the globe.

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 ??  ?? OUTBREAK: Emergency workers in Wuhan rush a patient into hospital
OUTBREAK: Emergency workers in Wuhan rush a patient into hospital

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