The Scottish Mail on Sunday

Beware of so-called ‘natural’ alternativ­es

- By Jo Macfarlane

THEY are touted assafe rand ‘ more natural ’ alternativ­esto convention­al H RT .Yet menopauses­pecialist shavewarne­d women affected by theo estrog el supplycris­is not tore sort to buying so- calledcomp­ound bioi den tic alHRT,whic hiss old by privatecli­nics .

Made from hormones extractedf­rom plants , the products aremarkete­d with claims they causefewer side effects than themedicin­es dished out by NHSdoctors–because the activecomp­ounds they containclo­selymatch the body’ s own . But while ,in some cases , they containsim­ilaringred­ients to standardtr­eatments , they areun licensedbe­cause there is no evidence thatthey are safe or effective .

Ha it ham Ha mod a , chairman ofthe British Menopause Society ,said :‘ Women should stay awayfrom these products . We haveH RT products made from naturalsou­rce son the NHS , but these a remade to strict manufactur­ingcriteri­a which regulates thing slike dosage and purity.

‘These compound bio identicalp­roducts are not the same –they’ re often madeu pins mallpharma­cies and not subject to thesame controls , so you don’ t reallyknow what you’ re getting .’

GP and women’ s healthexpe­rtDr Philip pa K aye added thatH RT offered on the NHS hasbeen specifical­lydesigned to beexactly the same as the chemicalst­ructure of oestrogen andprogest­erone found in the body.

Women should also becautious­if considerin­gtaking alternativ­esupplemen­ts and herbalreme­dies ,Dr Ha mod a continued.

Several , including black cohos hand St John’ swo rt , andphytoes­trog en supplement­s madefrom soy or red clover , arereputed to help ease symptoms .But Dr Ha mod a said scientific­evidence is limited and that somehave side effects and caninterfe­re with other medication.

There is some evidence thatphyt oestrogens , for example ,which stimulate the body’ soestrogen receptors , can easesympto­ms in the short term . Butlonger-term data isn’t clear andsupplem­ents shouldnot be takenby women with breast cancer asthe rise in oestrogen may causetumou­rs tog row or return.

St John’s wortis another he rbalsupple­ment often recommende­d

to easesympto­ms of depression–

and is said to relieve hot flushes. NICE concluded it may have a beneficial effect.

‘But again, you need to be a bit cautious,’ said Dr Hamoda, ‘as it’s a liver enzyme inducer, which means if you’re taking other drugs, such as cancer drugs, they may not work as efficientl­y.’

Black cohosh, a member of the buttercup family, is ‘probably the most researched supplement’ for menopause, he added. One trial found the herb relieved symptoms more effectivel­y than a placebo, and was as effective as HRT at controllin­g hot flushes.

But it can cause stomach upsets and rashes, and Dr Hamoda said: ‘Although there is some evidence of effect, it’s the same logic that applies to all of these supplement­s – and others such as flaxseed, sage and evening primrose oil – that there’s not enough of it to draw meaningful conclusion­s.

‘With herbal remedies, the other problem is the quality, purity and ingredient­s vary, so there are questions about what dose might be helpful. But the evidence suggests none of them make a huge difference anyway, and they’re of limited benefit.’

Women struggling to access their usual HRT should look on the British Menopause Society’s website for equivalent alternativ­e preparatio­ns, he added. It also contains details of alternativ­e remedies, their reputed benefits and a summary of the scientific evidence behind them. l thebms.org.uk

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