The Sunday Telegraph

Vampire therapy could help fight to beat dementia

- By Sarah Knapton SCIENCE EDITOR

IT MIGHT seem the stuff of fairytales, but a new trial has found that pumping the blood of young people into the elderly may help ward off the symptoms of dementia.

Scientists tried out the so-called “vampire therapy” after astonishin­g results three years ago showed that infusions of young blood into older mice formed new blood vessels and improved memory and learning.

For the new trial, 18 people over 65 with mild to moderate Alzheimer’s were given either four weekly infusions of plasma from people aged between 18 and 30, or a placebo. Although the phase one tests were only designed to prove that the procedure was safe, participan­ts reported a marked improvemen­t in Alzheimer’s symptoms.

Patients found it easier to carry out daily tasks such as rememberin­g to take medicine, paying bills or preparing meals. Dr Sharon Sha, associate professor of neurology at Stanford Uni- versity, who was the trial’s clinical lead, said she was not expecting such early positive results. She said: “Our enthusiasm concerning these findings needs to be tempered by the fact that this was a small trial. But these results warrant further study.”

Throughout history, many cultures have extolled the properties of youthful blood, with the blood of young warriors drunk by the victors. Scientists believe that young blood is so potent because it carries large quantities of a protein known as GDF111, which diminishes as we age.

There are estimated to be 850,000 people with Alzheimer’s in Britain. Dr Carol Routledge, director of research at Alzheimer’s Research UK said: “We need to see much larger studies before we can tell if this approach could help improve the lives of people living with Alzheimer’s disease.”

The research was presented this weekend at the 10th annual Clinical Trial on Alzheimer’s Disease conference in Boston.

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