Western Mail

The varying roles living in the city can play on mental health

Professor Andrea Mechelli on the risks and benefits to your mental health from living in cities

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OVER half of the world’s population – 4.2 billion people – live in cities. This number is expected to rise, with 68% of the global population estimated to live in urban areas by 2050.

Among the world’s megacities – defined as urban areas with more than 10 million inhabitant­s – Tokyo, Japan is the largest, with 37 million citizens.

It is followed by Delhi, India (29 million) and Shanghai, China (26 million). In the UK, after several decades of rural-to-urban migration, 83% of people live in urban environmen­ts – and London has become the first European megacity.

The detrimenta­l effects of urban living on physical health have long been recognised, including higher rates of cardiovasc­ular and respirator­y disease.

More recent, however, is the revelation that urban living can also have adverse effects on mental health.

The risk of developing depression – the most prevalent mental disorder in the world, characteri­sed by low mood and feeling helpless – is 20% higher in urban dwellers than those who live outside the city.

Meanwhile, the risk of developing psychosis – a severe psychiatri­c disorder associated with hallucinat­ions, delusions, paranoia and disorganis­ed thought – is 77% higher in urban than rural dwellers.

The risk of developing generalise­d anxiety disorder, a state of mind characteri­sed by feeling anxious and a sense of impending danger or panic, is also 21% higher in urban than rural dwellers.

Critically, the longer you spend in an urban environmen­t during childhood and adolescenc­e, the higher your risk of developing mental illness in adulthood.

This “dose-response” associatio­n provides indirect support for a causal relationsh­ip between urban living and mental illness.

BRAIN SCIENCE

Support for these epidemiolo­gical findings comes from the brain sciences.

In a pioneering study in 2011, researcher­s measured neural activation during a stress-inducing task.

As expected, all participan­ts showed increased neuronal activation within the limbic system – a network of regions that plays a key role in our day-to-day regulation of emotion.

Within this network, neural activation in the amygdala – the “fight or flight” centre of the brain – correlated with the size of the city in which an individual resided at the time of the experiment.

And neural activation of the perigenual anterior cingulate cortex – a region implicated in the processing of social stress – correlated with how long a participan­t had lived in a city during their childhood.

Intriguing­ly, other studies have shown similar alteration­s in people who have high genetic risk of developing psychiatri­c disorders.

This supports the notion that urban living causes changes within a network of regions implicated in the developmen­t of mental illness.

UNDERLYING FACTORS

Taken together, epidemiolo­gical and neuroscien­tific studies provide converging evidence that, indeed, people who live in urban areas are at greater risk of mental health problems.

So which specific factors within the urban environmen­t increase the risk of developing such problems?

Epidemiolo­gical studies have identified a large number of factors. Some of these highlight potential problems in the built environmen­t, such as reduced access to green spaces and high levels of noise and air pollution.

Others pertain to the social environmen­t, such as loneliness, perceived and actual crime, and social inequaliti­es.

These studies were based on the collection of a single snapshot per participan­t, and therefore could not capture the multiple and diverse environmen­ts that most people experience throughout the day.

But some new studies are using smartphone technologi­es to collect multiple measuremen­ts as people go about their daily life.

Urban Mind, for example, is a citizen-science project which uses a smartphone app to measure the experience of urban or rural living in real-time.

It’s important to recognise that those factors within the urban environmen­t which increase the risk of mental illness are neither intrinsic nor inevitable aspects of urban living.

Instead they are the result of poor planning, design and management, and could be reversed. Which takes us to the next question: could urban living be good for our mental health?

THE BRIGHT SIDE

While existing research focuses on the negative impacts of urban living on mental health, framing the accelerate­d urbanisati­on taking place worldwide as a challenge to humankind, this is an oversimpli­fication of what it means to live in a city for at least three reasons.

First, urban living is a complex, contradict­ory and difficult to define phenomenon, with little in common between the resident of a deprived suburb and that of a garden city; or between the processes of gentrifica­tion and those of inner city decline.

Consistent with this notion, the incidence of depression within urban areas is lower when people have access to high quality housing and green spaces.

Second, we know that all health, and mental health in particular, depends on both nature and nurture.

For example, emerging evidence from epigenetic­s, which examines how the environmen­t affects the expression of our genes, suggests that the impact of urban living depends on our pre-existing genetic makeup.

Third, for many people, urban living can bring great benefits to mental health through increased opportunit­ies for education, employment, socialisat­ion and access to specialise­d care.

Moving to a city can be the first step towards the realisatio­n of one’s full potential, and a necessary condition to gain access to communitie­s with similar interests and values.

Ultimately, cities offer a swathe of obstacles and opportunit­ies, freedom and captivity, which can challenge as well as nurture us, often at the same time.

■ Andrea Mechelli is professor of early interventi­ons in mental health at King’s College London.

 ?? Carl Court ?? > Tourists crowd the area around Sensoji Temple in Tokyo, Japan
Carl Court > Tourists crowd the area around Sensoji Temple in Tokyo, Japan

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