Yorkshire Post

Region’s researcher­s could have ‘huge impact’ on frailty in ageing

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MAJOR NEW research by Yorkshire scientists which could cut down the number of drugs people with various health conditions have to take in older age has been recognised at the European Parliament.

The developmen­t of a new class of drugs called geroprotec­tors could also delay the start of many age-related diseases, said Ilaria Bellantuon­o, Professor of Musculoske­letal Ageing at the University of Sheffield, inset.

She presented her work in Brussels as part of her role as the chair of the COST Action MouseAGE network, which met with European Parliament to urge all stakeholde­rs to work together to ensure the research and testing is fast-tracked. She said: “The occurrence of multiple diseases at the same time is one of the major health issues in older age. “Geroprotec­tors have the potential to delay the start of many age-related diseases at once and boost resilience in frail older people, reducing their need to take multiple drugs. “With people older than 60 expected to comprise 22 per cent of the global population by 2050, such drugs could be crucial in easing pressure on the health and social care systems.” Until now regulatory barriers and lack of research investment­s to support testing have prevented these drugs from reaching the clinic. The MouseAGE project represents 200 researcher­s from 25 EU counties, with expertise in ageing, age-related diseases and geriatrics and drug developmen­t.

Linda McAvan, MEP for Yorkshire and The Humber, said: “It’s great to see one of our local universiti­es leading the way in Europe on ground-breaking research into healthy ageing.

“This research into combating frailty could have a huge impact, enabling us all to live independen­tly for longer, have better physical and mental health and in turn reduce costs for the NHS and social care services.

“It is one of many EU-funded projects at local universiti­es, but what worries me is what happens after Brexit.

“I hope the Government will commit to continued UK participat­ion in such EU-wide projects so that we do not lose on the potential benefits such work offers for the British people.”

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