Scans show brains of aggressive teenagers are wired differently, say scientists

THE BRAINS of young people with the most severe forms of antisocial behaviour are “wired differently” to others – providing clues as to why they struggle to control and regulate their emotions, researchers say. In a study published today, neuroimaging methods were used to examine young people with conduct disorder – which has symptoms ranging from lying and truancy to physical violence and weapon use. Researchers from the universities of Bath, Cambridge and the California Institute of Technology set out to understand more about the wiring of the brain in adolescents with the condition. They used functional MRI scans of young people with conduct disorder, as well as typically developing teens, to analyse the amygdala – a key part of the brain involved in understanding the emotions of others – and how it communicates with other parts of the brain. Previous studies suggested that adolescents with the condition struggle to recognise angry and sad facial expressions and the latest research found they had significantly lower amygdala responses to them. They found those with conduct disorder showed abnormal connectivity between the amygdala and the brain’s prefrontal cortex – the region responsible for decision-making and behavioural inhibition. Researchers say the findings could help explain why young people with the condition struggle to control and regulate their emotions, which may make them more susceptible to developing anxiety or depression. Dr Graeme Fairchild, from the University of Bath’s department of psychology, said: “These results may explain why young people with conduct disorder, but without psychopathic traits, find it difficult to control their emotions – especially strong negative emotions like anger.” The study, published in journal was funded by The Wellcome Trust and the Medical Research Council.