Albany Times Union (Sunday)

Mistrust of vaccine could imperil immunity

Rushed timeline for developmen­t makes people wary

- By Jan Hoffman The New York Times

Almost daily, President Donald Trump and leaders worldwide say they are racing to develop a coronaviru­s vaccine, in perhaps the most urgent mission in the history of medical science. But the repeated assurances of near-miraculous speed are exacerbati­ng a problem that has largely been overlooked and one that public health experts say must be addressed now: persuading people to actually get the shot.

A growing number of polls find so many people saying they would not get a coronaviru­s vaccine that its potential to shut down the pandemic could be in jeopardy. Distrust of it is particular­ly pronounced in African-american communitie­s, which have been disproport­ionately devastated by the virus. But even many staunch supporters of immunizati­on say they are wary of this vaccine.

“The bottom line is I have absolutely no faith in the FDA and in the Trump administra­tion,” said Joanne Barnes, a retired fourth-grade teacher from Fairbanks, Alaska, who said she was otherwise always scrupulous­ly up-to-date on getting her shots, including those for shingles, flu and pneumonia. “I just feel like there’s a rush to get a vaccine out, so I’m very hesitant.”

Mistrust of vaccines has been on the rise in the U.S. in recent years, a sentiment that resists categoriza­tion by political party, educationa­l background or socioecono­mic demographi­cs. It has been fanned by a handful of celebritie­s. But now, antivaccin­e groups are attracting a new type of clientele altogether.

Jackie Schlegel, founder of Texans for Vaccine Choice, which presses for school vaccine exemptions, said that her group’s membership had skyrockete­d since April. “Our phones are ringing off the hook with people who are saying, ‘I’ve gotten every vaccine, but I’m not getting this one,’” she said. “‘How do I opt out?’” She said she often has to assure callers, “‘They’re not coming to your home to force-vax you.’”

The fastidious process to develop a safe, effective vaccine typically takes a decade; some have taken far longer. But the administra­tion of Trump, himself once an outspoken vaccine skeptic, has been saying recently that a coronaviru­s vaccine could be ready this fall. While it has removed certain convention­al barriers, such as funding, many experts still believe that the proposed timeline could be unduly optimistic.

But whenever a coronaviru­s vaccine is approved, the assumption has been that initial demand would far outstrip supply. The need to establish a bedrock of confidence in it has largely gone overlooked and unaddresse­d.

Earlier this month, a nationwide task force of 23 epidemiolo­gists and vaccine behavior specialist­s released a detailed report — which itself got little attention — saying that such work was urgent. Operation Warp Speed, the $10 billion public-private partnershi­p that is driving much of the vaccine research, they wrote, “rests upon the compelling yet unfounded presupposi­tion that ‘if we build it, they will come.’”

In fact, wrote the group, led by rese archers at th e Johns Hopkins Center for

Health Security and the Texas State University anthropolo­gy department: “If poorly designed and executed, a COVID-19 vaccinatio­n campaign in the U.S. could undermine the increasing­ly tenuous belief in vaccines and the public health authoritie­s that recommend them — especially among people most at risk of COVID-19 impacts.”

The researcher­s noted that although billions of federal dollars were pouring into biomedical research for a vaccine, there seemed to be virtually no funding set aside for social scientists to investigat­e hesitancy around vaccines. Focus groups to help pinpoint the most effective messaging to counter opposition, the authors said, should get underway immediatel­y.

The current political and cultural turbulence, abetted by the Trump administra­tion’s frequent disregard for scientific expertise, is only amplifying the diverse underpinni­ngs of vaccine-skeptic positions. They include the terrible legacy of federal medical experiment­s on African Americans and other disadvanta­ged groups; a distrust of Big Pharma; resistance to government mandates like school immunizati­on requiremen­ts; adherence to homeopathy and other “natural” medicines; and a clutch of apocalypti­c beliefs and conspiracy theories particular­ly around COVID-19, sometimes perpetuate­d by celebritie­s, most recently Kanye West.

“It’s so many of our children that are being vaccinated and paralyzed,” he told Forbes this month. “So when they say the way we’re going to fix COVID is with a vaccine, I’m extremely cautious. That’s the mark of the beast.”

A poll in May by The Associated PRESS-NORC Center for Public Affairs Research found that only about half of Americans said they would be willing to get a coronaviru­s vaccine. One in five said they would refuse and 31 percent were uncertain. A poll in late june by researcher­s at the University of Miami found that 22 percent of white and

Latino respondent­s and 42 percent of Black respondent­s said they agreed with this statement: “The coronaviru­s is being used to force a dangerous and unnecessar­y vaccine on Americans.”

“The trust issues are just tremendous in the Black community,” said Edith Perry, a member of the Maryland Community Research Advisory Board, which seeks to ensure that the benefits of health research encompass Black and Latino communitie­s.

The solution, she said, is not just to employ the convention­al strategy of meeting with Black church congregati­ons, especially if the government and vaccine producers want to reach millennial­s.

“The pharmaceut­ical industry would have to convince some of the young people in Black Lives Matter to get on board,” Perry said.

“Throw up your hands and say: ‘I apologize. I know we did it wrong and I need your help to get it right.’ Because we need a vaccine and we need Black and Hispanic participat­ion.”

 ?? Joel Saget / AFP via Getty Images ?? A lab technician wearing personal protective equipment takes reagent bottles to conduct vaccine tests at a French pharmaceut­ical company Sanofi’s laboratory in Val de Reuil.
Joel Saget / AFP via Getty Images A lab technician wearing personal protective equipment takes reagent bottles to conduct vaccine tests at a French pharmaceut­ical company Sanofi’s laboratory in Val de Reuil.

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