Texans Colts Lions Titans 49ers Cowboys

1 p.m. 1 p.m. 1 p.m.

Texans QB Deshaun Watson needs 239 yards passing for his second 4,000-yard season. He also has 25 TD passes, one short of his singleseason career high. … Houston WR Keke Coutee had eight receptions and a career-best 141 yards against Indy earlier this month.

Lions QB Matthew Stafford was unable to finish his latest game because of a rib injury. ... TE T.J. Hockenson leads Lions with 58 catches for 657 yards and has six TDS. … D’andre Swift and Jacksonville’s James Robinson are the NFL’S two rookie RBS with five rushing, two receiving TDS.

The Niners have multiple turnovers in seven straight games. ... The 49ers are one of four teams not to allow a 100-yard rusher this season. ... QB Nick Mullens has thrown for 4,186 yards in his first 15 starts, trailing only Patrick Mahomes and Kurt Warner.

Indy is tied for the AFC South lead with Tennessee but the Titans hold the tiebreaker based on current division records … The Colts have won two straight and six of their past eight overall. … DE Justin Houston had three sacks in the last matchup with the Texans.

The Titans are tied with Green Bay for the fewest turnovers with nine through 13 games. ... QB Ryan Tannehill completed a season-high 79.2 percent of his passes last week and had a 131.3 passer rating. ... RB Derrick Henry ran for a season-high 215 yards and two TDS last week.

The Cowboys have allowed a league-high 400 points (30.8 per game), 36 shy of the franchise record from 10 years ago. ... RB Ezekiel Elliott has just one 100-yard game this season. Elliott has four TDS (three rushing, one receiving) in two career games against the Niners.

Line: Pick:

Colts by 71⁄ Colts, 30-20

Line: Titans by 9 Pick: Titans, 30-22