Experimental COVID-19 vaccine is put to its biggest test
Results not expected until autumn
The biggest test yet of an experimental COVID-19 vaccine got underway Monday with the first of some 30,000 Americans rolling up their sleeves to receive shots created by the U.S. government as part of the all-out global race to stop the outbreak.
The glimmer of hope came even as Google, in one of the gloomiest assessments of the coronavirus’s staying power from a major employer, decreed that most of its 200,000 employees and contractors should work from home through next June — a decision that could influence other big companies.
Final-stage testing of the vaccine, developed by the National Institutes of Health and Moderna Inc., began with volunteers at numerous sites around the U.S. given either a real dose or a dummy without being told which.
“I’m excited to be part of something like this. This is huge,” said
Melissa Harting, a 36-year-old nurse who received an injection in Binghamton, New York. Especially with family members in front-line jobs that could expose them to the virus, she added, “doing our part to eradicate it is very important to me.”
It will be months before results trickle in, and there is no guarantee the vaccine will ultimately work against the scourge that has killed about 650,000 people around the world, including almost 150,000 in the U.S.
“We’ve been sitting on the sidelines passively attempting to wear our masks and social distance and not go out when it’s not necessary. This is the first step of becoming active against this,” researcher Dr. Frank Eder said at the trial site in Binghamton. “There’s really no other way to get past this.”
As if to underline how high the stakes are, there were more setbacks in efforts to contain the coronavirus.
In Washington, the Trump administration disclosed that national security adviser Robert O’Brien has the virus — the highest-ranking U.S. official to test positive. The White House said he has mild symptoms and “has been self-isolating and working from a secure location off site.”
The move to restart the national pastime ran into trouble just five days into the long-delayed season: Two major league baseball games scheduled for Monday night were called off as the Miami Marlins coped with an outbreak — the Marlins’ home opener against the Baltimore Orioles, and the New York Yankees’ game in Philadelphia, where the Marlins used the clubhouse over the weekend.
In Europe, rising infections in Spain and other countries caused alarm only weeks after nations reopened their borders in hopes of reviving tourism. Over the weekend, Britain imposed a 14-day quarantine on travelers arriving from Spain, Norway ordered a 10-day quarantine for people returning from the entire Iberian peninsula, and France urged its citizens not to visit Spain’s Catalonia region.
Scientists set speed records getting a made-from-scratch vaccine into massive testing just months after the coronavirus emerged. But they stressed that the public shouldn’t fear that anyone is cutting corners.
“This is a significant milestone,” NIH Director Francis Collins said after the very first test injection was given, at 6:45 a.m. in Savannah, Georgia. “Yes, we’re going fast, but no, we are not going to compromise” on proving whether the vaccine is safe and effective.
Several other vaccines made by China and by Britain’s Oxford University began smaller finalstage tests in Brazil and other hard-hit countries earlier this month. But the U.S. requires its own tests of any vaccine that might be used in the country.
Every month through the fall, the government-funded COVID-19 Prevention Network will roll out a new study of a leading candidate, each with 30,000 volunteers.