Arkansas Democrat-Gazette

Evidence shows effectiven­ess of AA

- AUSTIN FRAKT AND AARON E. CARROLL

For a long time, medical researcher­s were unsure whether Alcoholics Anonymous worked better than other approaches to treating people with alcohol use disorder. In 2006, a review of the evidence concluded we didn’t have enough evidence to judge.

That has changed.

An updated systematic review published recently by the Cochrane Collaborat­ion found that AA leads to increased rates and lengths of abstinence compared with other common treatments. On other measures, like drinks per day, it performs as well as approaches provided by individual therapists or doctors who don’t rely on AA’s peer connection­s.

What changed? The latest review incorporat­es more and better evidence. The research is based on an analysis of 27 studies involving 10,565 participan­ts.

The 2006 Cochrane Collaborat­ion review was based on just eight studies, and ended with a call for more research to assess the program’s efficacy. In the intervenin­g years, researcher­s answered the call. The newer review also applied standards that weeded out some weaker studies that drove earlier findings.

In the last decade or so, researcher­s have published a number of very high-quality randomized trials and quasi-experiment­s. Of the 27 studies in the new review, 21 have randomized designs. Together, these flip the conclusion.

“These results demonstrat­e AA’s effectiven­ess in helping people not only initiate but sustain abstinence and remission over the long term,” said the review’s lead author John F. Kelly, a professor of psychiatry at Harvard Medical School and director of the Recovery Research Institute at Massachuse­tts General Hospital. “The fact that AA is free and so widely available is also good news.

“It’s the closest thing in public health we have to a free lunch.”

Studies generally show that other treatments might result in about 15 percent to 25 percent of people who remain abstinent. With AA, it’s somewhere between 22 percent and 37 percent (specific findings vary by study). Although AA may be better for many people, other approaches can work too. And, as with any treatment, it doesn’t work perfectly all the time.

Rigorous study of programs like Alcoholics Anonymous is challengin­g because people self-select into them. Those who do so may be more motivated to abstain from drinking than those who don’t.

Unless a study is carefully designed, its results can be driven by who participat­es, not by what the program does. Even randomized trials can succumb to bias from self-selection if people assigned to AA don’t attend, and if people assigned to the control group do. (It may go without saying, but we’ll say it: It would be unethical to prevent people in a control group from attending Alcoholics Anonymous if they wanted to.)

Despite these challenges, some high-quality randomized trials of Alcoholics Anonymous have been conducted in recent years. One, published in the journal Addiction, found that those who were randomly assigned to a 12-step-based directive AA approach and were supported in their participat­ion attended more meetings and exhibited a greater degree of abstinence compared with those in the other treatment groups. Likewise, other randomized studies found that greater Alcoholics Anonymous participat­ion is associated with greater alcohol abstinence.

Alcoholics Anonymous is often paired with other kinds of treatment that encourage engagement with it. “For people already in treatment, if they add AA to it, their outcomes are superior than those who just get treatment without AA,” said Keith Humphreys, a Stanford University professor and co-author of the new Cochrane review.

Alcoholics Anonymous not only produced higher rates of abstinence and remission, but it also did so at a lower cost, the Cochrane review found. AA meetings are free to attend. Other treatments, especially those that use the health-care system, are more expensive.

One study found that compared with Alcoholics Anonymous participan­ts, those who received cognitive behavioral treatments had about twice as many outpatient visits— as well as more inpatient care—that cost just over $7,000 per year more in 2018 dollars. (Cognitive behavioral treatments help people analyze, understand and modify their drinking behavior and its context.)

Another study found that for each additional AA meeting attended, health-care costs fell by almost 5 percent, mostly a result of fewer days spent in the hospital and fewer psychiatri­c visits.

AA meetings are ubiquitous and frequent, with no appointmen­t needed; you just show up. The bonds formed from the shared challenge of addiction—building trust and confidence in a group setting—may be a key ingredient to help people stay on the road to recovery.

Worldwide, alcohol misuse and dependence are responsibl­e for 3.3 million deaths per year, 10 times the number of fatalities from all illicit drugs combined.

In the United States, alcohol is a larger killer than other drugs; accounts for the majority of all addiction treatment cases; and is responsibl­e for at least $250 billion per year in lost productivi­ty and costs related to crime, incarcerat­ion and health care. Moreover, American deaths related to alcohol more than doubled between 1999 and 2017.

Reducing the human and financial burdens of alcohol is an often overlooked public health priority, and the new evidence suggests that on balance one of the oldest solutions—Alcoholics Anonymous has been around almost 85 years — is still the better one.

Austin Frakt is director of the Partnered Evidence-Based Policy Resource Center at the V.A. Boston Healthcare System; associate professor with Boston University’s School of Public Health; and a senior research scientist with the Harvard T.H. Chan School of Public Health. Aaron E. Carroll is a professor of pediatrics at Indiana University School of Medicine and the Regenstrie­f Institute who blogs on health research and policy at The Incidental Economist and makes videos at Healthcare Triage.

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