Doctors question U.K.’s 12-week gap between shots
LONDON — A major British doctors’ group says the U.K. government should “urgently review” its decision to give people a second dose of the Pfizer-BioNTech coronavirus vaccine up to 12 weeks after the first, rather than the shorter gap recommended by the manufacturer and the World Health Organization.
The U.K., which has Europe’s deadliest coronavirus outbreak, adopted the policy in order to give as many people as possible a first dose of vaccine quickly. So far almost 5.9 million people in Britain have received a shot of either a vaccine made by U.S. drugmaker Pfizer and Germany’s BioNTech or one developed by U.K.-Swedish pharmaceutical giant AstraZeneca and Oxford University.
AstraZeneca has said it believes a first dose of its vaccine offers protection after 12 weeks, but Pfizer says it has not tested the efficacy of its jab after such a long gap.
The British Medical Association on Saturday urged England’s chief medical officer to “urgently review the U.K.’s current position of second doses after 12 weeks.”
In a statement, the association said there was “growing concern from the medical profession regarding the delay of the second dose of the Pfizer-BioNTech vaccine as Britain’s strategy has become increasingly isolated from many other countries.”
“No other nation has adopted the U.K.’s approach,” Dr. Chaand Nagpaul, chairman of the medical group’s council, told the BBC.
He said the WHO had recommended that the second Pfizer vaccine shot could be given up to six weeks after the first, but only “in exceptional circumstances.”
“I do understand the tradeoff and the rationale, but if that was the right thing to do, then we would see other nations following suit,” Nagpaul said.
Yvonne Doyle, medical director of Public Health England, defended the decision as “a reasonable scientific balance on the basis of both supply and also protecting the most people.”
Researchers in Britain have begun collecting blood samples from newly vaccinated people in order to study how many antibodies they are producing at different intervals, from 3 weeks to 24 months, to get an answer to the question of what timing is best for the shots.
The doctors’ concerns came a day after government medical advisers said there was evidence that a new variant of the virus first identified in southeast England carries a greater risk of death than the original strain.
Chief Scientific Adviser Patrick Vallance said Friday “that there is evidence that there is an increased risk for those who have the new variant,” which is also more transmissible than the original virus. He said the new strain might be about 30% more deadly, but stressed that “the evidence is not yet strong” and more research is needed.
Research by British scientists advising the government said although initial analyses suggested that the strain did not cause more severe disease, several more recent ones suggest it might. However, the number of deaths is relatively small, and fatality rates are affected by many things, including the care that patients get and their age and health, beyond having covid-19.
Britain has recorded 97,329 deaths among people who tested positive, the highest confirmed virus toll in Europe and the fifth-highest in the world.
The U.K. is in a lockdown to try to slow the latest surge of the virus, and the government says an end to the restrictions will not come soon. Pubs, restaurants, gyms, entertainment venues and many shops are closed, and people are required to stay largely at home.
HONG KONG LOCKDOWN
Meanwhile, thousands of Hong Kong residents were locked down in their homes Saturday in an unprecedented move to contain a worsening coronavirus outbreak in the city.
Authorities said an area comprising 16 buildings in the city’s Yau Tsim Mong district would be locked down until all residents were tested. Residents would not be allowed to leave their homes until they received their test results to prevent cross-infection.
“Persons subject to compulsory testing are required to stay in their premises until all such persons identified in the area have undergone testing and the test results are mostly ascertained,” the government said.
The restrictions, which were announced at 4 a.m. in Hong Kong, were expected to end within 48 hours, the government said.
Hong Kong has been grappling to contain a fresh wave of the coronavirus since November. More than 4,300 cases have been recorded in the past two months, making up nearly 40% of the city’s total.
Cases in Yau Tsim Mong district represent about half of the infections in the past week.
Approximately 3,000 people in Yau Tsim Mong had taken tests for coronavirus thus far, according to the Hong Kong government, joining the thousands of others around the crowded city of 7.5 million who have been tested in recent days.
Hong Kong has previously avoided lockdowns, with leader Carrie Lam stating in July that authorities would avoid taking such “extreme measures” unless they had no other choice.
The government appealed to employers to exercise discretion and avoid docking the salary of employees who have been affected by the new restrictions and may not be able to go to work.
Hong Kong has seen a total of 10,009 infections, with 168 deaths.