Arkansas Democrat-Gazette

Fully vaccinated sick, but experts see little to fear

Illness mostly shrugged off as shots work well, they say

- EMMA GOLDBERG

Although seemingly uncommon, some Americans are falling sick with the coronaviru­s even though they are fully immunized, in what are known as breakthrou­gh infections.

Public health experts continue to believe that these breakthrou­gh infections are relatively uncommon and rarely result in severe illness or hospitaliz­ations. The vaccines available in the U.S. offer powerful protection from serious covid illness, hospitaliz­ation and death. A recent analysis of state-reported data from the Kaiser Family Foundation found that more than 9 in 10 covid-19 cases that resulted in hospitaliz­ation and death occurred among people who were not fully vaccinated. “We always anticipate­d that there would be some breakthrou­gh infections, because the vaccines at their very best were 95% effective,” said Dr. William Schaffner, professor of infectious disease at Vanderbilt University. “The vaccines were designed to prevent severe illness, and they’re spectacula­rly successful at that.”

But as the more transmissi­ble delta variant becomes dominant in the U.S., rising numbers of breakthrou­gh cases are being reported, although most are mild.

For Moira Smith and her mother, July promised a glimmer of normalcy after months of isolation. The two flew from Alaska to Houston and visited relatives, celebratin­g the first birthday of their cousin’s granddaugh­ter.

Smith, 46, knew that her cousin’s family was not vaccinated but tried not to dwell on that. She and her mother had both received their Pfizer shots months earlier. In the hotel room one evening, Smith’s mother made an offhand comment to her relatives: “You can take your masks off, but you have to promise to get vaccinated,” she chided them.

The next morning Smith and her mother were headed home, on a layover in the Seattle airport, when they got the phone call: Their relative’s baby had come down with a fever and tested positive for the coronaviru­s.

Two days later, Smith woke up feeling like she had been “hit by a Mack truck,” with body aches and a sore throat, and tested positive for the coronaviru­s. The next week, her mother, who is 76 and has lung cancer, texted her an emoji of a thermomete­r indicating she, too, had spiked a fever, and she later wound up in the emergency room with covid.

Despite the threat to atrisk groups, like Smith’s mother, experts emphasize that the threat to the vaccinated is limited in scope.

“Delta is vastly more contagious, so as it is spreading among the unvaccinat­ed there is spillover into the vaccinated population,” Schaffner said. “The unvaccinat­ed are a big highway of transmissi­on. The vaccinated are a little side street.”

Because people infected with the delta variant have far more of the virus in the nose and upper respirator­y tract, the importance of mask-wearing has become paramount. After the Centers for Disease Control and Prevention shifted its guidance on masking, recommendi­ng that vaccinated people in hot-spot areas resume wearing masks in public indoor spaces, millions of Americans who are fully immunized struggled to adjust their expectatio­ns for the fall months that had seemed to offer some semblance of festivity. And a small subset of Americans already has seen their routines upended by breakthrou­gh infections.

Spurred by concerns about breakthrou­gh infections, federal health officials recently recommende­d that Americans who received the Pfizer or Moderna vaccines receive a third dose in the coming months. This week, Johnson & Johnson reported that a booster shot of its vaccine raised levels of antibodies against the coronaviru­s.

For some, breakthrou­gh infections have felt like mild allergies, coming with symptoms including a cough, sniffles and a scratchy throat. Others have had more severe cases, where they are bedridden with body aches, fevers and chills. And still others have had some of the telltale signs of covid such as loss of taste and smell, “covid rash” and brain fog.

“We were calling it floaty head syndrome,” said Molly O’Brien-Foelsch, 47, a marketing executive in Pennsylvan­ia who tested positive for the virus after a trip to the British Virgin Islands with her husband last month. “It felt like there was a huge marshmallo­w on my head.”

Scientists believe that breakthrou­gh infections rarely result in severe illness, but there have been cases of prolonged hospitaliz­ations.

Elaina Cary-Fehr’s father Isaac, 64, an Uber driver in Austin, Texas, was transferre­d to a long-term care facility after being hospitaliz­ed with covid pneumonia in June and later receiving a tracheotom­y tube. He was released from the facility this week.

“I believe in the vaccine, I kept holding on to hope that it would work and it did,” CaryFehr said. “But I hate that this had to happen to my family.”

As many Americans begin the familiar exercise of questionin­g and calling off plans, scientists are stressing the continued importance of mask-wearing to reduce transmissi­on and infection.

“If you get infected and breathe virus out, it will get trapped by your mask,” said John Moore, a professor of microbiolo­gy and immunology at Weill Cornell. “These viruses don’t have pairs of scissors that can cut through masks.”

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