Baltimore Sun Sunday

Fish oil drugs seem effective in heart’s health, 2 studies suggest

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Two major studies released Saturday provide evidence that medication­s derived from fish oil are effective in protecting people from fatal heart attacks, strokes and other forms of cardiovasc­ular disease.

The large, multiyear research efforts tested different formulatio­ns and quantities of drugs made with Omega-3 fatty acids on two groups of people: one that suffered from cardiovasc­ular disease or diabetes and another that represente­d the general population. Both studies found that people who took the drugs every day enjoyed protection against some heart and circulator­y problems compared with those given a placebo.

In a look at another commonly consumed supplement, vitamin D, researcher­s found no effect on heart disease but saw a link to a decline in cancer deaths over time.

The research was released Saturday at the American Heart Associatio­n’s 2018 Scientific Sessions in Chicago and published in the New England Journal of Medicine.

One of the studies unveiled Saturday, named by the acronym REDUCE-IT, determined that people with cardiovasc­ular disease who were already taking statins stood less chance of serious heart issues when they were also given two grams of the drug Vascepa twice a day.

The other fish oil study, called VITAL, looked at the effect of a different formulatio­n of Omega-3 fatty acids in a drug called Lovaza. The results suggested that people given the drug were 28 percent less likely to suffer heart attacks than those given a placebo and 8 percent less likely to have a variety of cardiovasc­ular events.

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