Baltimore Sun

Cancer cures depend on funds

- By Tom Sherman, Patricia Berg and Robert Weiner

With justificat­ions including “sequestrat­ion,” “shutdown,” and “furlough,” Congress has shifted the onus of funding cancer research, education and detection away from the federal budget, and onto its own citizens. According to Francis Collins, director of the National Institutes of Health, the agency has lost 25 percent of its purchasing power over the past decade, discouragi­ng American scientists from innovative research.

In Maryland the stakes are particular­ly high: According to the CDC, cancer is currently the second leading cause of death, accounting for nearly a quarter of all deaths. More than half of all counties in Maryland have population­s with “high” cancer rates (over 200 incidents per 100,000 people). Furthermor­e, in Baltimore City, cancer deaths occur at a rate 1.3 times higher than the national average.

A report released by the Maryland Cigarette Restitutio­n Fund shows that from 2001 to 2010, cancer diagnoses declined about two-thirds of a percent each year in the state. Mortality rates dropped almost 2 percent annually. The dramatic decline in deaths is attributed to medical technology, breakthrou­gh cancer detection research and aggressive public outreach on early screenings.

National cancer mortality rates have decreased by 30 percent nationwide over the past three decades.

If Americans do not want decades of medical progressio­n to reverse, they must urge Congress to change course quickly.

State Sen. C. Anthony Muse, a Prince George’s County Democrat, spearheade­d legislatio­n for the Maryland Department of Health to investigat­e cancer clusters within the state and find environmen­tal causes, such as tobacco use, weight, diet, industry or exposures to chemicals.

When Senator Muse’s committee reported recommenda­tions to the state legislatur­e earlier this year, members found that, “collective­ly these environmen­tal factors are involved to some degree in 2 of 3 (67 percent) cancers, both alone and in combinatio­n with inherited factors.” The report urges Maryland to “collaborat­e with academic institutio­ns and federal agencies” in order to expand prevention strategy efforts and educate at-risk population­s.

None of this can be done without funding. The current NIH disease categories spending report reveals that, as a whole, cancerrela­ted funding has been slashed 23 percent since 2010. As the NIH works with functional budget levels akin to Fiscal Year 2008, the agency is forced to balance limited resources with the costs of staying at the cutting edge of world-class scientific research.

During a debate on the House floor last spring, House Minority Whip Steny Hoyer, a Maryland Democrat, said reductions to the National Institutes of Health and other institutio­ns with innovative genomics and cancer research programs, such as Johns Hopkins University, is a “stupid, harmful, future-hurting and America under-cutting policy.”

Long-term cancer research is vital. A research team at the George Washington University Berg Laboratory discovered that a gene, known as BP1, is activated in 80 percent of breast cancer incidents. The team also found that the gene is activated in 70 percent of prostate cancer tumors, as well as in 63 percent of acute myeloid leukemia cases. Other researcher­s have found the gene highly activated in lung and ovarian cancer. Without sustained support, current knowledge of the BP1 gene would be non-existent.

Victories in cancer research are not reason to abandon the support that caused them.

“We are throwing away probably half of the innovative, talented research proposals that the nation’s finest biomedical community has produced,” Dr. Collins said.

The U.S. must not allow cancer to regain a strangleho­ld and outsource scientific research leadership to other countries. Rather than declaring past falling death rates as good enough, Congress should act aggressive­ly and recommissi­on the fight to eradicate the disease.

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