Baltimore Sun

UM opens cancer lab named for O’s owner Angelos’ sister

Research expected to lead to ‘groundbrea­king findings’

- By Andrea K. McDaniels amcdaniels@baltsun.com twitter.com/ankwalker

The University of Maryland School of Medicine has opened a cancer research laboratory named after the sister of Orioles owner Peter Angelos.

Angelos donated $1 million toward the Fannie Angelos Cellular Therapeuti­cs Lab. His sister died in 2015 at age 88 from myelodyspl­astic syndrome, a bone cancer.

The lab will focus on immunother­apy, a treatment in which a patient’s own immune cells, or T cells, are geneticall­y engineered to recognize and attack a cancer.

Scientists there also will develop cellbased therapies and cancer vaccines to stimulate the immune system to kill other kinds of cancer cells and study ways to engineer cells for other illnesses, including diabetes and heart disease.

“This new laboratory has the potential to yield groundbrea­king findings, not only for scientists studying cancer but for many other discipline­s as well,” said Dr. E. Albert Reece, dean of the medical school, in a statement.

The lab, part of the Marlene and Stewart Greenebaum Comprehens­ive Cancer Center, will allow scientists to work in-house. In the past, they have relied on outside facilities and other academic institutio­ns for geneticall­y modified cells to treat patients in clinical trials.

Medical school executives were joined by Gov. Larry Hogan for a ceremonial opening of the lab Monday. Hogan received treatment for lymphoma at the University of Maryland Medical Center in 2015.

“Having our own cell-processing laboratory will increase our ability to offer novel and promising cell-based therapies to our patients,” said Dr. Aaron P. Rapoport, the lab’s director and professor of medicine at the medical school, in a statement. “It will also help our investigat­ors move their basic and preclinica­l research into the clinic more quickly so that patients may benefit from our discoverie­s.”

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