Greinke silences Bucs

Zack Greinke’s bid for his first career no-hitter was thwarted by Pittsburgh’s Gregory Polanco’s leadoff home run in the eighth inning and the Arizona Diamondbacks held on to beat the Pirates, 2-1.

Greinke (4-2), who dominated the Pirates with a vicious slider, allowed that one hit in eight innings. He struck out 11 and walked one, and faced the minimum through seven innings. Rockies 10, Dodgers 7 — In Denver, Jeff Hoffman struck out eight to earn his first major league win, Carlos Gonzalez showed signs of breaking out of a slump with a two-hit, three-RBI night and Colorado held off visiting Los Angeles.

Reds 3, Giants 2 — Zack Cozart had two extra-base hits, including an RBI double in the top of the eighth inning that scored the game-winner, as Cincinnati won in San Francisco.

The Giants lost despite a four-hit game from center fielder Denard Span in his first game since coming off the disabled list. They are an MLB-worst 12-24.

American League

Royals 6, Rays 0 — Major league ERA leader Jason Vargas went seven more scoreless innings, Salvador Perez had a two-run double during a five-run eighth inning and Kansas City beat Tampa in St. Petersburg, Fla.

Jorge Bonifacio hit an RBI single off Diego Moreno in the decisive eighth before Whit Merrifield had a run-scoring single and then circled the bases when center fielder Kevin Kiermaier misplayed the hit for a three-base error. Astros 3, Yankees 2 — Defensive replacement Jake Marisnick made a perfect throw from left field to nail Jacoby Ellsbury at the plate for the final out and visiting Houston held off New York in a matchup between teams with the best records in baseball.

Unbeaten Dallas Keuchel (6-0) became the first six-game winner

in the majors, helped by a home run from Carlos Correa. The Astros (24-11) are off to their best start since the franchise began playing in 1962. Blue Jays 7, Mariners

2— Steve Pearce hit a three-run home run, Justin Smoak had a solo homer and finished with four RBI, and host Toronto stopped Seattle, snapping the M’s winning streak at four.

Marco Estrada (2-2) allowed two runs over six innings for the Blue Jays, who have won four of five.

Tigers 7, Angels 1 — In Anaheim, Calif., Justin Upton hit a three-run homer and Michael Fulmer pitched seven innings of three-hit ball as Detroit beat Los Angeles. Mike Trout went 0-for-4 as the Angels’ designated hitter after missing five straight games and six of the previous seven with a tight left hamstring. Twins 7, White Sox 6 — Eduardo Escobar hit a three-run homer then added a fourth RBI with a double as visiting Minnesota outlasted struggling Chicago, which nearly recovered from a 6-0 second-inning deficit. Brandon Kintzler struck out Omar Narvaez and Leury Garcia in the eighth with the tying run on third and go-ahead run on second.

Interleague

Rangers 5, Padres 2

— Mike Napoli’s second homer was a game-ending three-run shot and Texas dropped San Diego in Arlington, Texas.

The Rangers had been held scoreless by San Diego starter Clayton Richard until Napoli hit a 433foot homer to left on the first pitch of the eighth.

Napoli topped that with a 448-foot shot into the club-level seats higher in left field to end a four-run ninth off Padres closer Brandon Maurer (0-2).

Orioles-Nationals, ppd.

— The game between Baltimore and host Washington was postponed by rain. It was rescheduled for June 8.