Boston Herald

Poo Britannia

Researcher­s track UK variant of coronaviru­s in wastewater

- By Rick Sobey

Cambridge-based researcher­s have detected the more contagious U.K. variant in coronaviru­s wastewater samples, a “potentiall­y pretty significan­t” breakthrou­gh that could help officials shift vaccines to areas with more highly infectious variants, a leading epidemiolo­gist tells the Herald.

Researcher­s at Biobot Analytics — which has been tracking COVID-19 sewage samples in Greater Boston — have identified the B.1.1.7 variant in wastewater samples across the U.S., the company announced Wednesday.

“Launching B.1.1.7 analysis is the first step in a wastewater-based epidemiolo­gy approach that will expand to other variants as the COVID-19 pandemic evolves,” Mariana Matus, Biobot CEO and co-founder, said in a statement.

Biobot’s national network of community partners will now have informatio­n about the presence of the more contagious variant in their regions, the company said.

The scientists are also continuing research and developmen­t for other variants of concern.

The U.K. variant detection developmen­t has not yet been peer-reviewed, noted Boston University epidemiolo­gy professor Matthew Fox.

“But if the method is determined to indeed to be valid, it could be really helpful and potentiall­y pretty significan­t,” Fox said. “Wastewater surveillan­ce has been underutili­zed but has done a good job of predicting changes in the COVID-19 curve.

“So if we could also use it to detect shifts in variants, it could also allow for faster action,” he added. “If we could shift vaccines to areas with more highly infectious variants and also take public health action, we could prevent them from spreading.”

The CDC variant tracker shows a total of 686 confirmed U.K. variant cases in Massachuse­tts. But the sequence analysis has been “limiting,” said Davidson Hamer, a Boston University specialist in infectious diseases.

“This should be some great supplement­al informatio­n to give us an idea of the proportion of B.1.1.7. in the area,” he said of the research breakthrou­gh.

“Right now we’re in a race to get the vaccine out to as many people as possible before this strain really affects more people,” Hamer added. “It’s definitely more transmissi­ble.”

Results in Massachuse­tts Water Resources Authority’s study to track COVID-19 in Greater Boston wastewater spiked in January.

Biobot Analytics is now accepting and analyzing wastewater samples for the

U.K. variant, and plans to add additional variants to its analysis as methods are developed.

The Cambridge-based company is working on this effort with Singapore-MIT Alliance for Research and Technology (SMART), MIT’s Research Enterprise in Singapore.

 ?? STuART CAHILL / HeRALd sTAFF FILe ?? NEW CLUE: Cambridge researcher­s have detected the British variant of coronaviru­s in wastewater samples.
STuART CAHILL / HeRALd sTAFF FILe NEW CLUE: Cambridge researcher­s have detected the British variant of coronaviru­s in wastewater samples.

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