Browns remain winless

ORCHARD PARK, N.Y. (AP) — LeSean McCoy scored on a 21-yard run with 1:33 left in overtime to secure the Buffalo Bills' 13-7 win over the Indianapolis Colts in a wintry, white-out setting best suited for snow shoes and sled dogs.

McCoy finished with 156 yards rushing and topped the 1,000-yard mark for the sixth time in his career on a slick, snow-covered field.

The Bills' sideline erupted after McCoy's touchdown, with numerous players running on to the field to either make snow angels or engage in celebratory snowball fights.

Buffalo (7-6) stayed alive in the AFC playoff picture, while the Colts (3-10) were mathematically eliminated from playoff contention.

The game began in nearly white-out conditions with a major lake-effect storm blowing in off nearby Lake Erie. The snow fell so hard a half-hour before kickoff it was nearly impossible to see New Era Field's west-end scoreboard from the east-end stands.

McCoy's touchdown came on Buffalo's second possession of overtime. Facing third-and2, McCoy found a crease up the middle and had enough footing to cut to his left and scamper into the end zone untouched.

EAGLES 43, RAMS 35

LOS ANGELES (AP) — Carson Wentz threw for 291 yards and four touchdowns before leaving with a knee injury, and Jake Elliott kicked the go-ahead 33-yard field goal with 3:45 left as the Eagles clinched the NFC East title.

Two sources familiar with the injury tell The Associated Press that doctors believe Wentz has torn his left anterior cruciate ligament and will miss the rest of the season and playoffs.

Wentz needs an MRI to confirm the severity of the injury. Both people spoke to the AP on condition of anonymity because they weren't authorized to release the information.

Wentz was hit hard as he scrambled into the end zone on a play that was called back because of holding. He stayed in the game and threw a 3-yard touchdown pass to Alshon Jeffery four plays later to give the Eagles the lead. Foles replaced Wentz on the next drive for Philadelphia (11-2). The NFC West-leading Rams (9-4) then went up 35-31 on Todd Gurley's second short TD run.

JAGUARS 30, SEAHAWKS 24

JACKSONVILLE, Fla. (AP) — Blake Bortles threw two perfect passes for touchdowns and Jaydon Mickens set up another score with a 72-yard punt return.

The Jaguars (9-4) intercepted three passes by Russell Wilson, including two on deep balls, and won for the sixth time in their last seven games. This victory, coupled with Tennessee's loss at Arizona, moved Jacksonville atop the AFC South.

It's the first time since 2010 that the Jaguars have had the outright division lead this late in a season.

The loss didn't sit well with the Seahawks (8-5), who had two players ejected in the final minute. Defensive tackle Sheldon Richardson was ejected for throwing a punch during a melee that included defensive tackle Michael Bennett and Jaguars running back Leonard Fournette.

CARDINALS 12, TITANS 7

GLENDALE, Ariz. (AP) — Phil Dawson kicked four second-half field goals and the Cardinals shut down Tennessee's offense nearly all day.

Dawson connected from 47, 23, 32 and 35 yards and missed from 40 for the Cardinals (67), whose victory came two weeks after they beat then-AFC South leader Jacksonville on the same field.

The Cardinals intercepted Marcus Mariota twice in the second half after the Titans (8-5) nursed a 7-0 lead at halftime.

CHARGERS 30, REDSKINS 13

CARSON, Calif. (AP) — Philip Rivers passed for 319 yards and two touchdowns, and the Chargers continued their ferocious playoff push with their fourth straight victory.

Tyrell Williams caught a 75-yard touchdown pass and Hunter Henry had another scoring grab for the Chargers (7-6), who have won seven of nine after an 0-4 start to their relocation season.

While outscoring their opponents 131-53 during their winning streak, the Chargers also moved above .500 for the first time since September 2015 with a dominant offensive performance against Washington.

The Chargers stayed atop the AFC West alongside the Chiefs (7-6), their opponents Saturday in Kansas City. Kirk Cousins hit Vernon Davis with an early TD pass for the Redskins (5-8), who have lost two straight and six of eight.

PACKERS 27, BROWNS 21

CLEVELAND (AP) — Brett Hundley threw a 25-yard touchdown pass to Davante Adams in overtime as the Packers rallied from a two-touchdown deficit in the fourth quarter.

Cleveland fell to 0-13 and made too many crucial mistakes to break into the win column.

CHIEFS 26, RAIDERS 15

KANSAS CITY, Mo. (AP) — Kareem Hunt ran for 116 yards and a touchdown and the Chiefs shut down Derek Carr and his offense to snap a four-game losing streak.

The suddenly stingy Chiefs (7-6) also made a big statement in the crowded AFC West race. They are tied atop the division with the Chargers; the Raiders are 6-7.

The Chargers visit Kansas City on Saturday night.

Alex Smith threw for 268 yards and Charcandrick West had a touchdown run for the Chiefs, who held the Raiders without points until Marshawn Lynch's 22-yard run with 8:51 to go.

PANTHERS 31, VIKINGS 24

CHARLOTTE, N.C. (AP) — Jonathan Stewart ran for 103 yards and three touchdowns, and the Panthers snapped the Vikings' eight-game winning streak.

Cam Newton threw for a touchdown and ran for 75 yards as the Panthers (9-4) racked up 216 yards on the ground against the league's No. 2 ranked defense to pull even with the Saints atop the NFC South standings.

Carolina sacked Case Keenum six times and forced three turnovers to keep the Vikings (103) from clinching the NFC North division title.

After the Panthers squandered an 11-point fourth-quarter lead, Newton broke free of the pocket and raced 62 yards for a key first down with 2:00 remaining. Stewart scored his careerhigh third TD when he jumped over the line of scrimmage, reaching the ball across the goal line for the winning points.

Minnesota couldn't manage a first down on its final drive and turned over the ball on downs.

COWBOYS 30, GIANTS 10

EAST RUTHERFORD, N.J. (AP) — Dak Prescott threw three touchdown passes and the desperate Cowboys spoiled Steve Spagnuolo's debut as interim coach, as well as the return of quarterback Eli Manning to the Giants' starting lineup.

Prescott threw a go-ahead 20-yard score to tight end Jason Witten with 7:38 to play. Rod Smith scored on an 81-yard pass play with 4:08 left and added a 15-yard scoring run a little more than a minute later after an interception by Sean Lee.

Prescott, who was 20 of 30 for 332 yards, also threw a 50-yard scoring pass to Dez Bryant as the Cowboys (7-6) stayed in the playoff hunt with three games left in the regular season. Dan Bailey added a 21-yard field goal as the Cowboys finished with 454 yards. New York fell to 2-11. Manning, who got a standing ovation taking the field, threw a 1-yard TD pass to Rhett Ellison late in the second quarter that gave New York a brief 10-3 lead.

Manning finished 31 of 46 for 228 yards with a touchdown and two late interceptions.

BRONCOS 23, JETS 0

DENVER (AP) — The Broncos snapped their longest losing streak since joining the NFL in 1970 thanks to wide receiver Demaryius Thomas' big game and a return of Denver's stingy defense.

Trevor Siemian threw for 200 yards and his favorite target was Thomas , who caught eight passes for 93 yards and a touchdown as the Broncos (4-9) avoided tying their franchise futility record of nine consecutive losses set way back in 1967.

This was their first win in 70 days — and their first shutout since Nov. 20, 2005, a 27-0 win over the Jets.

It was fueled by a defense that held New York in check all afternoon.

The Jets (5-8) were limited to 100 yards of offense, 59 on the ground and 41 through the air. Jets quarterback Josh McCown was knocked from the game twice by hard hits, including a clean shot by pass rusher Shane Ray in the third quarter that left McCown with a broken left hand.

LIONS 24, BUCCANEERS 21

TAMPA, Fla. (AP) — Matthew Stafford passed for 381 yards with an injured throwing hand and set up Matt Prater for a 46-yard field goal in the closing seconds.

Stafford made his 109th consecutive start despite being limited in practice after his right hand was stepped on during the previous week at Baltimore. He completed 36 of 44 attempts against the Bucs (4-9), and the Lions (7-6) overcame two interceptions and a fumble to stop a two-game losing streak.

Jameis Winston rallied Tampa Bay, which has lost eight of 10 following a 2-1 start, with a pair of fourth-quarter TD passes. But once again, the Bucs' defense couldn't hold off an opponent down the stretch.

49ERS 26, TEXANS 16

HOUSTON (AP) — Jimmy Garoppolo threw for a career-high 334 yards and a touchdown to help the 49ers to their second straight win.

Garoppolo again showed that he could be the answer for the 49ers (3-10) at quarterback, going 20 of 33 in his second start for the team. Acquired before the trade deadline from New England, Garoppolo threw for 293 yards in his debut last week to help the 49ers to a 15-14 win at Chicago.

BEARS 33, BENGALS 7

CINCINNATI (AP) — Rookie Mitchell Trubisky threw for a touchdown and ran for another in his best showing yet, and the Bears ended a five-game losing streak with their most lopsided victory in five years.