Call & Times

Now that media has stopped lying for them, China should answer how covid-19 began

- The Washington Post

Three years after the initial outbreak in Wuhan, China, the origins of the coronaviru­s pandemic are still a mystery. The latest reports of a shift in the conclusion of one U.S. intelligen­ce agency – for reasons that have not been disclosed – underscore the uncertaint­y. What is clear is that answers exist in China, and that finding them requires far more investigat­ion than has been carried out so far, which Beijing has refused to allow. What is China hiding, and why? Two broad hypotheses exist about the origins of covid-19. One is that it jumped from a natural source, probably a bat, perhaps through an intermedia­te animal host, to infect people. This has ample precedent in earlier viral pandemics. Bats are a reservoir for coronaviru­ses and live in Southeast Asia, albeit those in China are located far from Wuhan. But no samples – none – have turned up to identify the animal source or the intermedia­te host. There were positive samples detected in the Huanan Seafood Market, where wildlife was sold, but they were likely from infected humans, not animals. The market was quite clearly the venue of an early supersprea­der event.

The other hypothesis is that some kind of research-related incident or inadverten­t laboratory leak allowed the virus to escape. Large numbers of bats were captured by Chinese researcher­s for study at the Wuhan Institute of Virology, a major center of research on bat coronaviru­ses. Other Chinese scientific research centers also worked on coronaviru­ses and vaccines.

A very curious research proposal in 2018 by EcoHealth Alliance, a nongovernm­ental organizati­on in New York, outlined plans to geneticall­y modify chimeric viruses – that is, those with genetic material from two or more different viruses – to add a feature known as a furin cleavage site, which helps infect cells. The feature exists on the pandemic strain, but not in the immediate family of other bat coronaviru­ses. (It exists on other coronaviru­ses, such as MERS.) Some of the proposed research was to take place at the Wuhan institute. The research proposal was turned down by the Defense Advanced Research Projects Agency, but a question that persists is whether the work went ahead anyway at the Wuhan institute. The institute claims that its collection did not include the pandemic strain so it could not have been the source. But very little is known about the research being conducted there, or in other laboratori­es in China.

A third, plausible explanatio­n might lie between these two – for instance, that a researcher was accidental­ly infected handling a bat during laboratory work and spread the virus.

On Sunday, the Wall Street Journal reported this was the Energy Department, which shifted from being noncommitt­al to concluding, with “low confidence,” that the virus originated from a laboratory. Also, on Tuesday, FBI Director Christophe­r A. Wray publicly confirmed the agency’s classified conclusion of a possible laboratory origin.

All of this suggests that we need to know more.

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