Chicago Sun-Times

Winfrey takes ‘ Henrietta’ to heart

True story makes science accessible, personal on HBO

- Andrea Mandell @ andreamand­ell USA TODAY

Oprah Winfrey became obsessed with Henrietta Lacks’ story along with the rest of the world in 2010, but she never intended to star in HBO’s movie version, The Immortal Life of Henrietta Lacks ( Saturday, 8 ET/ PT).

“For years, I was like, ‘ I don’t want to do it. I don’t want to take this on. I just want to be a producer,’ ” says Winfrey, from her home in Montecito, Calif.

But she ended up taking a lead role as Lacks’ daughter, Deborah, after optioning the rights to produce a film based on the 2010 bestseller. The book chronicles how the African- American cancer patient from Baltimore died in 1951, not knowing her tumor cells were harvested by researcher­s at Johns Hopkins Hospital. Henrietta’s cells, knowns as HeLa, later were duplicated into “immortal” cell lines used by scientists for medical testing all over the world.

Author Rebecca Skloot’s nearly 400page tome proved difficult to adapt. The non- fiction work weaves the story of Lacks’ descendant­s, many of whom couldn’t afford health insurance despite their mother’s medical contributi­ons; HeLa’s effect on scientific breakthrou­ghs, from the polio vaccine to cancer research; and the ethical repercussi­ons of sampling body tissue without patients’ consent.

Early on, “there were some versions ( of the script) where it was mostly science, and I was falling asleep,” Winfrey says. “We know, obviously, that getting people to digest science is a very difficult thing. Like, ‘ Yes, you will enjoy spinach with a broccoli sauce.’ Being able to put it in a form where it is accessible and actually meaningful was the challenge.”

And Skloot gets it. “It took me 11 years to turn it into a book,” says the author, who had to persuade the Lacks family to

“Being able to put ( science) in a form where it is accessible and meaningful was the challenge.” Oprah Winfrey, who plays Deborah Lacks

trust her after they’d been burned by others hoping to profit from their story. ( The family remains divided on the HBO film.)

Winfrey’s tune changed when director George C. Wolfe ( Nights in Rodanthe) rewrote the script to focus on Deborah and her quest to learn about what happened to her mother inside the then- segregated walls of Johns Hopkins.

“The biotech industry was born on the use of Henrietta Lacks’ cells,” Wolfe says. “HeLa is this incredible medical phenomenon. And then a few blocks away, there was a family that knew nothing about it.”

Rose Byrne ( who “failed” biology and was a “miserable” science student) signed on to play Skloot, whose work “encompasse­s a lot of things: the line between science and ethics, race in America,” she says.

Renée Elise Goldsberry, just off a Tony- winning run in Hamilton, plays Henrietta in flashbacks. “I feel like I’m watching Oprah do this beautiful job of risking her sanity to uncover some potentiall­y painful informatio­n,” she says, noting how Deborah found the courage to open up to Skloot despite having “been so betrayed so many times.”

For Winfrey, the story brought back her early career. In eight years as a reporter in Baltimore, “I never once heard the name Henrietta Lacks,” she says.

It’s why she’s put her stamp on the story.

“My inclinatio­n is to share informatio­n,” says Winfrey. “I find a thing; I like it, ( I share it): ‘ You gotta know about this thing!’ So I was excited for as many people to know about Henrietta Lacks as I could reach.”

 ?? QUANTRELL COLBERT, HBO ?? Rose Byrne and Oprah Winfrey star in HBO’s The Immortal Life of Henrietta Lacks, based on the best- selling book about a cancer patient’s legacy. Winfrey plays Lacks’ daughter.
QUANTRELL COLBERT, HBO Rose Byrne and Oprah Winfrey star in HBO’s The Immortal Life of Henrietta Lacks, based on the best- selling book about a cancer patient’s legacy. Winfrey plays Lacks’ daughter.
 ??  ?? Renée Elise Goldsberry plays Henrietta Lacks in flashbacks in the new HBO film, premiering Saturday.
Renée Elise Goldsberry plays Henrietta Lacks in flashbacks in the new HBO film, premiering Saturday.
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