Chicago Sun-Times

HOW TO SAFELY INCREASE LEVELS OF PROTEIN IN DIET

- BY DR. ELIZABETH KO AND DR. EVE GLAZIER Dr. Eve Glazier is an internist and assistant professor of medicine at UCLA Health. Dr. Elizabeth Ko is an internist and primary care physician at UCLA Health.

Dear Doctor: I recently read about a woman who died from a protein overdose. Is it really possible to have too much protein? How much are we supposed to be eating?

Dear Reader: We remember the news story you’re referring to as it caused quite a stir. A bodybuilde­r from Australia, who had put herself on a high- protein diet in order to prepare for a competitio­n, was found unconsciou­s in her home. She passed away two days later. Although the cause of death was listed as “intake of bodybuildi­ng supplement­s,” the story is actually more complicate­d. An autopsy revealed that the woman had a rare genetic condition that made it impossible for her body to efficientl­y digest protein. Known as urea cycle disorder, it’s a deficiency in one of the enzymes in the liver that scrubs the blood of nitrogen, a waste product of protein metabolism.

When the urea cycle is functionin­g properly, nitrogen is removed from the blood, converted to urea, and transferre­d to the urine for eliminatio­n. But in individual­s with urea cycle disorder, the nitrogen accumulate­s in the tissues in the form of ammonia, which is extremely toxic. Ammonia is carried through the blood to the brain, where irreparabl­e damage can occur.

Though there is no cure at this time, the condition can be managed through diet and various medication­s and supplement­s. In the case of the bodybuilde­r, her disorder was undiagnose­d. It had been mild enough that, when she ate normally, she didn’t have any serious problems. However, when she upped her protein intake to prepare for the competitio­n, she inadverten­tly pushed her body beyond the limits of what it could manage. As a result, the ammonia in her blood reached fatal levels.

When it comes to recommenda­tions on how much protein we should eat, there is a bit of debate. According the Recommende­d Dietary Allowance ( RDA) in the United States, it’s 0.8 gram of protein for every kilogram of weight. And for us in the non- metric U. S., that’s 0.36 grams of protein per pound of weight. Age and activity level play a part as well. The U. S. Department of Agricultur­e has a nifty online calculator: http://www.nal.usda.gov/fnic/interactiv­eDRI/.

Most of us who eat a balanced diet will have no problem meeting the RDA for protein. For very active individual­s, elite athletes, or those working to lose weight or build muscle, more protein may be advisable. On the other side of the spectrum, people living with kidney disease must take care not to eat too much protein. A high- protein diet can impair kidney function due to the increase in waste products from protein metabolism.

Some nutrition researcher­s believe the RDA for protein should be increased to slightly more than the current recommenda­tions. Until that debate gets resolved, the RDA is our best guide. For anyone who wants to increase his or her protein intake, we recommend consulting with a nutritioni­st or sports medicine specialist for informatio­n and guidance.

 ?? | STOCK. ADOBE. COM ?? According the Recommende­d Dietary Allowance ( RDA) in the United States, 0.36 grams of protein per pound of weight is the recommende­d amount of dietary protein intake.
| STOCK. ADOBE. COM According the Recommende­d Dietary Allowance ( RDA) in the United States, 0.36 grams of protein per pound of weight is the recommende­d amount of dietary protein intake.
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