Chicago Tribune (Sunday)

Report points to 4 theories in origin of virus

- By Daria Litvinova and Jamey Keaten

GENEVA — A team of internatio­nal and Chinese scientists is poised to report on its joint search for the origins of the coronaviru­s that sparked a pandemic after it was first detected in China over a year ago — with four theories being considered, and one the clear front-runner, according to experts.

The lengthy report is being published after months of wrangling, notably between U.S. and Chinese government­s, over how the outbreak emerged, while scientists try to keep their focus on a so-far fruitless search for the origin of a microbe that has killed more than 2.7 million people and stifled economies.

It wasn’t clear when the report will be released after its publicatio­n was delayed this month. By many accounts, the report could offer few concrete answers, and may raise further questions.

It will offer a first glance in writing from 10 internatio­nal epidemiolo­gists, data scientists, veterinary, lab and food safety experts who visited China and the city of Wuhan — where a market was seen as the initial epicenter — this year to work with Chinese counterpar­ts who pulled up the bulk of early data.

Critics have raised questions about the objectivit­y of the team, insisting that China had a pivotal say over its compositio­n. Defenders of the World Health Organizati­on, which assembled the team, say it can’t simply parachute in experts to tell a country what to do — let alone one as powerful as China.

“I expect that this report will only be a first step into investigat­ing the origins of the virus and that the WHO secretaria­t will probably say this,” said Matthew Kavanagh, director of Georgetown

University’s Global Health Policy and Governance Initiative at the O’Neill Institute. “And I expect some to criticize this as insufficie­nt.”

The Wuhan trip is billed as Phase 1 in a vast undertakin­g to flesh out the origins of the virus.

The WHO has bristled at depictions of the mission as an “investigat­ion,” saying that smacks of an invasive forensic probe that wasn’t called for under the resolution adopted unanimousl­y by the agency’s member states in May that paved the way for the collaborat­ion. The WHO and China later ironed out the ground rules.

Team member Vladimir Dedkov, an epidemiolo­gist and deputy director of research at the St. Petersburg Pasteur Institute in Russia, summarized the four main leads first laid out at a marathon news conference in China last month about the suspected origins of the

first infection in humans.

They were, in order of likelihood: from a bat through an intermedia­ry animal; straight from a bat; via contaminat­ed frozen food products; from a leak from a laboratory like the Wuhan Institute of Virology.

Officials in China, as well as Chinese team leader Liang Wannian, have promoted the cold-chain one, while the U.S. administra­tion under President Donald Trump played up the lab leak. But Dedkov said those two hypothesis were far down the list of likely sources.

He suggested frozen products on which the virus was found were most likely contaminat­ed by infected people. An infected person also likely brought and spread the virus at the Wuhan market associated with the outbreak, where some of the contaminat­ed products were later found.

“In general, all the conditions

for the spread of infection were present at this market,” Dedkov said. “Therefore, most likely, there was a mass infection of people who were connected by location.

“At this point, there are no facts suggesting that there was a leak” from a lab, Dedkov said. “If suddenly scientific facts appear from somewhere, then accordingl­y, the priority of the version will change. But, at this particular moment, no.”

Suspicions about political meddling have dogged the mission, and the internatio­nal team leader — the WHO’s Peter Ben Embarek — acknowledg­ed last week that unspecifie­d “pressures” might weigh on its members.

Liang, in a Chinese newspaper interview, also bemoaned political pressure on the team.

Delays in deploying the internatio­nal team to China, repeated slippage in the timing of publicatio­n of

the report, and rejiggerin­g of the plans for it — an initial summary of findings was jettisoned as an idea — have only fanned speculatio­n that the scientists have been steered by political authoritie­s or others.

“The last understand­ing we had was that it is expected to come out this week — we’ll have to see if that actually happens,” the U.S. charge d’affaires in Geneva, Mark Cassayre, said Wednesday.

He said the U.S. was hopeful the report would be a “real step forward for the world understand­ing the origins of the virus, so that we can better prepare for future pandemics. That’s really what this is about.”

The WHO leadership, including Director-General Tedros Adhanom Ghebreyesu­s, repeatedly praised the Chinese government’s early response to the outbreak, though recordings of private meetings obtained by The

Associated Press exposed how top WHO officials were frustrated at China’s lack of cooperatio­n.

The internatio­nal team was reliant on data collected by Chinese scientists after the outbreak surfaced, and Dedkov called the visit to Wuhan an “analytical trip, mainly for the purpose of retrospect­ive analysis in the sense that we studied only those facts that were obtained earlier.”

“We did not collect any samples ourselves, we didn’t carry out any laboratory studies there, we just analyzed what we were being shown,” he said. If some data had not been collected, it wasn’t because the Chinese wanted to conceal something, he added.

The team’s visit was politicall­y sensitive for China, which is concerned about any allegation­s it didn’t handle the initial outbreak properly. Shortly after the outbreak, the Chinese government detained some doctors who sought to raise the alarm.

The report, which Ben Embarek said last week took up about 280 pages, is set to lay out recommenda­tions and lay the groundwork for next steps — such as whether the team, or others, get new access to China for further analysis. Ultimately, the aim is to find clues to help prevent another pandemic.

Georgetown’s Kavanagh said he hasn’t seen the report — but has suspicions about what it will say.

“Based on what we have heard so far I expect that the report will likely lend some credence to a link between wildlife farming and COVID-19, but without full evidence about exactly how the move from animals into humans might have occurred,” he said.

Dedkov said planning of “real-time research” is next, but noted there’s no guarantee future trips will find all the answers.

 ?? NG HAN GUAN/AP ?? A worker walks last month by the Wuhan Central Hospital, where Li Wenliang once worked. He was the whistleblo­wer doctor who sounded the alarm and was reprimande­d by local police in the early days of the pandemic.
NG HAN GUAN/AP A worker walks last month by the Wuhan Central Hospital, where Li Wenliang once worked. He was the whistleblo­wer doctor who sounded the alarm and was reprimande­d by local police in the early days of the pandemic.

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