China Daily Global Edition (USA)

Scientist cleared of falsifying results

- By ZHANG ZHIHAO zhangzhiha­o@chinadaily.com.cn

An investigat­ion into scientist Han Chunyu, who was forced to retract a paper he wrote about a groundbrea­king gene-editing technique after allegation­s of fraud, has concluded that he did not intentiona­lly falsify his research.

The news triggered some skepticism and debate online regarding academic integrity.

Han’s employer, Hebei University of Science and Technology in Shijiazhua­ng, Hebei province, said it had joined with third-party labs to conduct thorough investigat­ions and repeated experiment­s regarding the data and findings presented in the paper, according to a short online statement released on Friday night.

The statement said the investigat­ion found no evidence that Han, an associate professor of biology, and his team had subjective­ly or intentiona­lly falsified their research, but said the retracted paper could not be republishe­d. All titles, awards and grants given to Han as a result of the paper have been revoked, it added.

In a statement on Saturday, Han and his team accepted the results of the investigat­ion and conceded that their research had design flaws and issues regarding accuracy. “While unexpected errors can occur in research, we apologize to the scientific community and the public for causing unnecessar­y trouble,” they said.

In comments, netizens said they are skeptical of the school’s findings, criticizin­g its use of vague terms, lack of supporting data and attempts to trivialize the incident.

Zhao Jianfei, deputy chief editor of the New England Journal of Medicine’s Frontiers of Medical Science, said the investigat­ion failed to answer key questions, including why Han initially insisted on the feasibilit­y of his research to the media but later backpedale­d, according to quotes in The Intellectu­al, an online media platform for Chinese scientists.

In May 2016, Han shocked the global science community when he published his paper, which focused on a more effective alternativ­e to the popular CRISPR-Cas9 genome editing technique. The paper was published in the prestigiou­s scientific journal Nature Biotechnol­ogy.

In the paper, Han described how he had successful­ly used an enzyme called NgAgo to edit specific human genes with great accuracy, allowing for the possibilit­y of creating designer babies with traits favorable to the eliminatio­n of cancers and genetic diseases.

The media and scientific peers initially hailed the discovery and portrayed Han as an underdog because he was an unremarkab­le scientist from a poorly funded lab.

Overnight, the public, the government and the school showered Han with praise and grants.

However, his fame faded as quickly as it arrived because peers, from schools as far apart as Australia and Spain, could not reproduce the results.

In the face of media inquiries, Han avoided answering key questions and claimed that some labs had reproduced his results. He also blamed unsuccessf­ul trials on inaccurate methods or polluted samples.

He later retracted his claim after many scientists, both at home and abroad, were unable to duplicate his work despite a year of efforts.

The issue drove discontent among the scientific community. Han voluntaril­y retracted his paper in August last year.

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