CLEVELAND (7-3) AT JACKSONVILLE (1-9)

Sunday, 1 p.m. OPENING LINE: Browns by 6½ SERIES: Jags, 12-5 LAST MEETING: Jags, 19-7, 2017 FANTASY TIP: With Jacksonville down so many defenders, it should be a good week to get every Browns player possible into your starting lineup. ETC.: Cleveland’s 7-3 record is its best after 10 games since starting 8-2 in 1994 under Bill Belichick. … QB Baker Mayfield has not thrown an interception in three games. … Jacksonville placed three defensive starters – end Josh Allen, cornerback D.J. Hayden and safety Daniel Thomas – on injured reserve this week. Already-depleted unit also will be without three coaches.

NEW ORLEANS (8-2) AT DENVER (4-6)

Sunday, 4:05 p.m. OPENING LINE: Saints by 5½ SERIES: Broncos, 9-2 LAST MEETING: Broncos, 2523, 2016 FANTASY TIP: Broncos WR Tim Patrick has topped 100 yards three times this season, including last week when he had five receptions for 119 yards vs. Dolphins. ETC.: Saints’ Alvin Kamara ranks second in NFL with 1,179 scrimmage yards (648 receiving, 531 rushing) and last week became first player with at least 500 yards rushing and receiving in each of his first four seasons. ... QB Drew Lock leads AFC with 11 interceptions.

SAN FRANCISCO (4-6) AT L.A. RAMS (7-3)

Sunday, 4:05 p.m. OPENING LINE: Rams by 6½ SERIES: 49ers, 72-67-3 LAST MEETING: 49ers, 24-16 on Oct. 18 FANTASY TIP: Cooper Kupp has been targeted 40 times in the last three games for 27 catches and 305 yards. ETC.: 49ers have lost three straight games by at least 10 points for the first time since final three games of their 0-9 start in 2017. ... San Francisco is 1-6-1 following a bye the past eight seasons. ... Jared Goff has passed for 300 yards in three straight games after doing it twice in the Rams’ first seven games.

KANSAS CITY (9-1) AT TAMPA BAY (7-4)

Sunday, 4:25 p.m., CBS OPENING LINE: Chiefs by 3 SERIES: Bucs, 7-5 LAST MEETING: Bucs, 19-17, 2016 FANTASY TIP: Bucs’ Mike Evans is tied for fourth in NFL with nine TD receptions. He had six catches for 105 yards in only game he’s played vs. Chiefs. ETC.: Chiefs have won five straight games. It’s the eighth consecutive year they have had a streak at least that long. ... Chiefs WR Tyreek Hill has TD receptions in each of the past four games. ... Bucs have lost two of three following a 6-2 start that was the team’s best since 2002.

CHICAGO (5-5) AT GREEN BAY (7-3)

Sunday, 8:20p.m., NBC OPENING LINE: Packers by 7½ SERIES: Packers, 99-95-6 LAST MEETING: Packers, 2113, 2019 FANTASY TIP: Bears already rank next to last in NFL in yards per game and have an uncertain QB situation, making this a good week to take a chance on Green Bay’s defense. ETC.: Chicago’s Cordarrelle Patterson has scored on eight career kickoff returns to share NFL record with Josh Cribbs and Leon Washington. … Packers lead the NFL in average time of possession (32:27). … Packers have allowed only 12 sacks this season.

BALTIMORE (6-4) AT PITTSBURGH (10-0)

Tuesday, 8 p.m., NBC OPENING LINE: Steelers by 5 SERIES: Steelers, 29-24 LAST MEETING: Steelers, 2824 on Nov. 1 FANTASY TIP: K Justin Tucker has been excellent against the Steelers, making all 30 of his extra-point attempts and 46 of 48 field-goal attempts. ETC.: Steelers are 17th team since 1970 to start 10-0. ... Pittsburgh leads NFL in fewest points allowed (17.4 per game). Baltimore is third (19.5). ... Steelers coach Mike Tomlin ranks second and Ravens coach John Harbaugh is fifth in winning percentage among active NFL coaches.