Daily News (Los Angeles)

Pfizer to buy Bay Area blood company for $5.4B

Fat with cash, the pharmaceut­ical giant wants treatment for sickle cell disease

- By Tom Murphy And Michelle Chapman

Pfizer will spend about $5.4 billion to buy Global Blood Therapeuti­cs as the pharmaceut­ical giant continues to invest some of the cash influx reaped during the COVID-19 pandemic.

Pfizer said Monday the acquisitio­n will boost its work in rare hematology. Global Therapeuti­cs, which was founded in 2011 and is based in south San Francisco, makes Oxybryta tablets for treating sickle cell disease.

Pfizer has been flush with cash since its COVID-19 vaccine, Comirnaty, and its treatment, Paxlovid, have hit the market, starting with the vaccine in late 2020. The drugmaker has now announced deals valued at a total of nearly $19 billion, counting debt, since late last year.

The latest deal follows Pfizer's $11.6 billion acquisitio­n of Biohaven, which the companies announced in May, and a $6.7 billion acquisitio­n of Arena Pharmaceut­icals announced last December.

Pfizer also detailed in April a smaller acquisitio­n of the privately held ReViral Ltd., which is developing a treatment for respirator­y syncytial virus.

Pfizer Inc.'s vaccine and treatment brought in more than $16 billion combined just in the recently completed second quarter. Comirnaty rang up nearly $37 billion in sales last year alone, but those sales are expected to fade in a few years. Pfizer also faces over the next decade the loss of patent protection for key products such as Eliquis for preventing blood clots and strokes.

The company plans to have about $25 billion in sales by 2030 come from new business developmen­ts.

Aamir Malik, the company's chief business innovation officer, told analysts recently that Pfizer was “leaving very few stones unturned” in looking for expansion opportunit­ies. Malik said Pifzer was looking for deals that will add substantia­l value either scientific­ally or commercial­ly.

“I think we're very excited about the opportunit­ies that are ahead of us and the flexibilit­y that our balance sheet gives us to pursue those,” he said during a call to discuss second-quarter results.

Malik told analysts that the Biohaven deal alone could add $6 billion in peak sales to Pfizer's business.

The drugmaker said Monday that the sickle cell disease franchise of Global Blood Therapeuti­cs, which includes treatments still in developmen­t, could eventually reach worldwide peak sales of more than $3 billion.

Oxbryta sales were about $195 million last year, but Pfizer said it plans to speed up distributi­on of the drug to parts of the world most affected by the disease.

Sickle cell disease is an inherited blood disorder that can lead to bouts of acute pain and organ damage. It occurs particular­ly among people of African descent. The companies say there are 4.5 million people living with the disease globally.

Pfizer will pay $68.50 per share in cash for each share of Global Blood Therapeuti­cs. That represents a premium of nearly 43% from the stock's closing price of $47.99 on Thursday, the day before The Wall Street Journal reported that Pfizer was in advanced talks on a deal.

Both companies' boards have approved the deal, which still needs regulatory approval and approval from GBT shareholde­rs. The companies say the deal could close as soon as the fourth quarter.

Shares of Global Blood Therapeuti­cs rose more than 4% to $66.58 in morning trading. Broader indexes and shares of New York-based Pfizer climbed slightly.

 ?? MARK LENNIHAN THE ASSOCIATED PRESS ?? Pfizer is buying sickle cell drugmaker
Global Blood Therapeuti­cs in a deal approximat­ing
$5.4 billion as it looks to accelerate growth
after its revenue soared during the
pandemic. Both companies' boards have approved the
deal, which still needs regulatory
approval and approval from GBT
shareholde­rs.
MARK LENNIHAN THE ASSOCIATED PRESS Pfizer is buying sickle cell drugmaker Global Blood Therapeuti­cs in a deal approximat­ing $5.4 billion as it looks to accelerate growth after its revenue soared during the pandemic. Both companies' boards have approved the deal, which still needs regulatory approval and approval from GBT shareholde­rs.

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