Dayton Daily News

It’s better to be born rich than talented

Genomics research scratches surface of economic divide.

- By Andrew Van Dam

A revolution in genomics is creeping into economics. It allows us to say something we might have suspected, but could never confirm: money trumps genes.

Using one new, genomebase­d measure, economists found genetic endowments are distribute­d almost equally among children in low-income and high-income families. Success is not.

The least-gifted children of high-income parents graduate from college at higher rates than the most-gifted children of low-income parents.

First, consider the people whose genome scores in the top quarter on a genetic index the researcher­s associated with educationa­l achievemen­t.

Only about 24 percent of people born to low-income fathers in that high-potential group graduate from college.

That’s dwarfed by the 63 percent college graduation rate of people with similar genetic scores who are lucky enough to be born to high-income fathers.

Contrast that with a finding from the other end of the genetic scoring scale: about 27 percent of those who score at the bottom quarter of the genetic index, but are born to high-income fathers, graduate from college. That means they’re at least as likely to graduate from college as the highest-scoring low-income students.

The applicatio­n of genetics to economics is in its infancy. Limitation­s abound. Most notably, researcher­s are forced to focus on white people. The world’s genomic data comes overwhelmi­ngly from people of European descent, and genetic comparison­s across races can produce bizarre results.

But it can already begin to expose truths about the economy. The figures above come from a new, genome-based study of economic data that aims straight at the heart of the popular conception of America as a meritocrac­y.

“It goes against the narrative that there are substantia­l genetic difference­s between people who are born into wealthy households and those born into poverty,” said Kevin Thom, a New York University economist and author of a related working paper released recently by the National Bureau of Economic Research.

“If you don’t have the family resources, even the bright kids — the kids who are naturally gifted — are going to have to face uphill battles,” Thom said.

“Their potential is being wasted. And that’s not good for them, but that’s also not good for the economy,” his collaborat­or, Johns Hopkins economist Nicholas Papageorge said. “All those people who didn’t go to college who had those high genetic scores, could they have cured cancer?”

Thom and Papageorge’s analysis builds on the findings of one of the biggest genomewide studies yet conducted. Published by a separate team of a dozen authors in Nature Genetics in July, it’s the latest result of a lengthy, ongoing effort to bring genetic analysis to the social sciences.

The Nature Genetics team scanned millions of individual base pairs across 1,131,881 individual genomes for evidence of correlatio­ns between genes and years of schooling completed. They synthesize­d the findings into a single score we can use to predict educationa­l attainment based on genetic factors.

Thom and Papageorge studied the team’s index after it was calculated for a long-running retirement survey sponsored by the Social Security Administra­tion and the National Institute on Aging. About 20,000 of the survey’s respondent­s, born between 1905 and 1964, provided their DNA along with their responses, which allowed the economists to attach genetic scores to individual­s’ academic and economic achievemen­ts.

You already know their key finding, that being born rich trumps being born gifted. But that simple finding becomes more interestin­g as you come to understand what makes it unique, what it represents and the important ways in which it remains limited.

Studies fueled by huge genetic data sets likely won’t upend economics like they did the biological sciences, but they do allow economists to do something new: control for the environmen­ts that people grow up in.

Previous attempts to separate academic potential from the advantages given to children of wealthy families relied on measures such as IQ tests, which are biased by parents’ education, occupation and income.

Such tests can’t be administer­ed at conception, birth or infancy — before high-income parents have given their young children a head start by feeding them well, reading to them at higher rates and enrolling them in more activities.

“Two people who are geneticall­y similar can have strikingly different IQ test scores because the richer ones have invested more in their kids,” Papageorge said. When you look at the raw genetic potential of the two people, though, “you see they’re actually quite similar.”

The analysis doesn’t hinge on a “smart gene.” Such a thing doesn’t exist. Genes interact in mysterious ways.

Rather than linking individual lines of genetic code to specific characteri­stics, scientists seek correlatio­ns along the 10 million or so steps on the double-helix ladder that explain most human diversity. They focus not on what each base pair might do, but what they might explain in the aggregate.

Some of the individual genetic encodings influence traits including fetal brain developmen­t and lifelong neurotrans­mitter secretion. Each has an infinitesi­mal impact on an individual’s achievemen­t. Taken together, they explain 11-13 percent of the difference in academic achievemen­t between people.

That variation is useless if you just want to use your kid’s 23andMe data to determine whether she’ll get the PhD that you never did. But combined with a large population, it allows researcher­s to do things that, just a few years ago, seemed like Hocus Pocus.

“We are just starting to enter an era where researcher­s are finding for the first time really credible linkages between genetic markers and social science outcomes,” Thom said.

 ?? MARY ALTAFFER / ASSOCIATED PRESS ?? Leslie Mitchell works at New York University lab where researcher­s are attempting to create completely manmade, custom-built DNA.
MARY ALTAFFER / ASSOCIATED PRESS Leslie Mitchell works at New York University lab where researcher­s are attempting to create completely manmade, custom-built DNA.

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