Biotech company 10X Genomics plans big expansion

Project would be built at Pleasanton strip mall in phases ending in 2030

PLEASANTON >> A growing biotech company, Pleasanton-based 10X Genomics Inc., plans to build an expanded operation at the Pleasanton Plaza strip mall where the Cost Plus World Market is located.

The 14.58- acre site at 1701 Springdale Ave. is sandwiched between Stoneridge Mall to the north, Kaiser medical offices to the west and a mix of residences to the east. 10X Genomics manufactures gene sequencing used for scientific research and “builds products to interrogate, understand and master biology to advance human health,” according to the company’s website, which notes its research also involves COVID-19.

The expansion would entail demolishing 163,500 square feet of commercial buildings, including the Cost Plus, and rezoning the area from commercial to commercial- office space. The company wants to construct three multistory buildings totaling 381,000 square feet and a parking structure, according to a city staff report.

The new campus would go up in phases as needed until fully completed by 2030, the report says.

“The existing retail center has been operating at this location since the early 1980s but has suffered from lack of investment and has struggled to maintain occupancy of its tenant spaces,” the report adds.

10X Genomics’ current headquarters would remain on Stoneridge Mall Road near Interstate 680, about a half-mile from the proposed expansion.

The first phase would involve razing the commercial structures and constructing a 100,000-square-foot, 38-foot-tall building, a new plaza and a pedestrian path connecting the campus to the mall and nearby BART station. This phase, to be completed in one to two years, would also include 400 parking spaces.

Other phases, to be built when needed, would include construction of at least two buildings with a combined 281,000 square feet and a 60-foot-tall parking structure with 1,180 parking spaces in six levels.

The project was introduced to the Planning Commission at a workshop last month and is expected to be presented to it in late spring for a possible recommendation to the City Council. The city is currently reviewing the application and an accompanying environmental analysis of potential impacts such as traffic.

10X Genomics also has offices in San Francisco, the Netherlands, Sweden, Singapore and Shanghai.