Cubs knock off Padres 6-5.

CHICAGO (AP) — Before Friday's game against San Diego, a 9-year-old boy named Mateo met Anthony Rizzo in the Chicago Cubs' dugout and gave him a note asking for a "moonshot" on behalf of group attending a charity running event of the Anthony Rizzo Family Foundation this weekend.

Rizzo followed with a go-ahead grand slam, his first home run since June 15.

"That was for him," Rizzo, a Hodgkin's lymphoma survivor, said after the Cubs overcame a three-run deficit to beat the Padres 6-5. "That's really special for him to come and hang out there."

Javier Báez also homered for the NL Centralleading Cubs, who have won six of seven since the All-Star break. Chicago overcame an early home run by Manny Machado that built a 3-0 lead.

Josh Naylor tied the score 5-5 in the eighth inning against Pedro Strop (2-3) with his first career pinch homer, but the Cubs went back ahead in the bottom half.

Rizzo singled off Craig Stammen (6-5), rookie shortstop Fernandez Tatis Jr. threw Addison Russell's grounder into center field for an error, Jason Heyward was intentionally walked and David Bote hit a grounder to third. Machado threw home for a forceout and catcher Francisco Mejia threw to first, even though he didn't have a play on Bote. The ball hit off the glove of first baseman Eric Hosmer and bounced into short right field as Rizzo scored on Hosmer's error.

"A couple young guys playing really fast, trying to do special things, and sometimes those plays just aren't there," Padres manager Andy Green said. "If you're going to make mistakes in the field, mistakes of aggression are the better kind of mistakes."

Craig Kimbrel struck out three around a four-pitch walk in the ninth for his fifth save in six chances. San Diego has lost five of six and 11 of 15.

Jon Lester made his 400th big league appearance and matched his career high by allowing 12 hits, giving up four runs in six innings. He needed 26 pitches to get through the first on a 93 degree day.