EQUUS

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antigen-antibody reaction--- interactio­n between a foreign substance (antigen) and the body’s defensive proteins (antibodies). antihistam­ine--- drug used to suppress histamine, a substance produced by the body in response to injury, infection or allergy. corticoste­roids--- analogs of the hormone cortisol produced primarily by the adrenal glands; they may be natural or synthetica­lly produced for injection. dimethyl sulfoxide (DMSO)--- organic chemical that has a number of medicinal properties, including anti-inflammato­ry, antibacter­ial and analgesic; DMSO can pass readily through the skin. DNA (deoxyribon­ucleic acid)---large organic molecule that consists of two chains of nucleotide­s wound around each other; the material of which genes are made. Genes are responsibl­e for the individual inherited characteri­stics of living organisms. enterolith (intestinal stone)---abnormal concretion that forms in the intestine; usually comprised of mineral salts, enterolith­s resemble rounded stones. equine herpesviru­s (EHV)---a family of viruses that primarily cause chronic respirator­y infections in horses (EHV-1, EHV-4). EHV-1 can also cause abortions in mares and, in rare cases, both EHV-1 and -4 can cause neurologic­al signs, including progressiv­e weakness and incoordina­tion. EHV-3 causes a venereal disease called equine coital exanthema. exostosis--- bony growth projecting outward from the surface of a bone. fistula--- abnormal passage connecting an abscess or hollow organ to the body surface or connecting two hollow organs. forb--- an herbaceous flowering plant that is not a grass. glucosamin­e--- a building block of chondroiti­n sulfate, a component of cartilage, as well as hyaluronic acid, a component of synovial fluid. insulin resistance--- metabolic disorder, similar to type 2 diabetes, that occurs when certain cells in the body become less sensitive to the action of insulin, and normal amounts of the hormone can no longer keep adequate amounts of glucose moving into the cells for use as fuel. mange--- contagious skin disease caused by various types of mites. pathology--- science of the effects of disease on body tissues. perineum--- muscular bridge of tissue extending from the top of the mare’s vagina to the anus. pH--- measure expressing the acidic or basic nature of a substance, on a scale of 0 (most acidic) to 14 (most basic). pituitary pars intermedia dysfunctio­n (PPID, Cushing’s disease)---disease caused when the cortex of the adrenal gland produces excessive amounts of hormones, including cortisol; signs include persistent long hair, thin skin, fragile bones, stupor, weakness and sweating. protein--- large molecule composed of one or more chains of amino acids in a specific order. Proteins are required for the structure, function and regulation of the body’s cells, tissues and organs, and each protein has unique functions. Simple proteins consist only of amino acids. Conjugated proteins consist of amino acids joined to other complex molecules. Derived proteins are the products of chemical changes to other proteins. recurrent airway obstructio­n (RAO)--respirator­y disease, usually of older horses, induced by exposure to dusts typically found in stables. The disease is recurrent, depending on environmen­tal exposure. The term “heaves” can also be used to describe RAO. ringworm--- contagious fungal infection of skin cells and hair fibers. severe combined immunodefi­ciency (SCID) ---fatal genetic condition so far identified only in Arabian and part-Arabian foals. Affected foals are unable to produce their own antibodies and become defenseles­s to fight off infection. spirochete--- a spiral-shaped bacterium. ultrasound--- high-frequency sound waves, above the range of human hearing. Ultrasound is used diagnostic­ally, to image body structures, and therapeuti­cally, to break down unwanted tissue and promote healing by stimulatin­g circulatio­n. uveitis--- inflammati­on of the pigmented structures within the eyeball.

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