THE frost folio
through Opko health, frost is building a health-care-focused berkshire hathaway, but like other great investors he finds values in a myriad of industries.
OPKO health frost owns 34% of therapeutics and diagnostics company with $1.2 billion in sales.
teva Pharmaceuticals industries a $20 billion (revenue) Israel-based big pharma, specializing in generics. frost owns 1.5% of the stock.
Vector GROUP founded by fellow Philadelphian bennett lebow; owns tobacco company liggett Group and commercial realtor Douglas elliman Realty. frost is largest shareholder, with 15%.
LADENBURG thalmann Regional investment bank and financial advisory; 4,000 advisors and $132 billion in assets. frost owns 36.5% and vector Group owns 8.23%. castle brands Maker of premium liquor, including Jefferson’s whiskey and Goslings rum. frost owns 33.5% and vector 8%. coconut GROVE bankshares Miami-dade’s oldest bank; frost owns 24%. cogint formerly Tiger Media; a cloud-based data and analytics company focused on marketing and risk management. frost owns 29%. biocardia formed by frost’s Sorbonne roommate, Dr. Simon Stertzer. a clinical-stage company using stem cells to repair cardiac muscle after a heart attack. frost owns 32.7%. DRONE aviation florida-based maker of drones for law enforcement and military. frost owns 14%. arno therapeutics Developing antiprogestins for breast, endometrial and prostate cancers. opko owns 9%.
Zebra BIOLOGICS attempting to make generic versions of antibody drugs—like the bestselling rheumatoid arthritis drug Humira—that could be better than the original. opko owns 29%. OAO Pharmsynthez Russian developer and marketer of new drugs in eastern europe. opko owns a 17% equity interest. rxi Pharmaceuticals ladenburg took it public in December. Developing an Rna interface to prevent skin scars. opko has an 19% equity interest. cocrystal Pharma new antivirals (hepatitis C, flu, norovirus); frost and opko own 23%. SEVION therapeutics Developing antibodies against difficult targets; treating cancer and immunological diseases. frost and opko own 20%. NEOVASC Canadian maker of specialized cardiology devices. frost owns 22%. CHROMADEX Maker of ingredients for nutritional supplements. frost owns 14.6%. Vbi Vaccines Developing a technology platform to design vaccines for hepatitis b, Zika and brain tumors. opko has a 25% equity interest. Mabvax therapeutics Clinical-stage cancer immunotherapy. frost and opko have an estimated 5% interest. MUSCLEPHARM nutritional supplements. frost owns less than 5%.