Greenwich Time

Good news with vaccines, but keep wearing a mask

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The news that not just one, but two new vaccines hold promise for great efficacy against the coronaviru­s is cause for optimism. We are eager for the long nightmare of mounting deaths, sickness, social isolation and uncertaint­y to be over soon.

But the realizatio­n of that hope is still a long ways away. Now is not the time to let down our guard.

We’re in the eighth inning, is how former federal Food and Drug Administra­tion Commission­er and Westport resident Scott Gottlieb put it to Gov. Ned Lamont recently. But the inning could be long and the “game” is far from over.

First the hope. Pfizer, which has a research and developmen­t facility in Groton, announced Wednesday its vaccine, in its third phase of trials, shows a 95 percent effectiven­ess at protection from the virus. That is above the 90 percent initially reported and much higher than most vaccines against other illnesses. The company, which developed the vaccine with Germany-based BioNTech, said it had the necessary two months of safety data required to seek emergency use authorizat­ion from the FDA and will do so in a matter of days.

While the efficacy rate was consistent across age, gender, race and ethnicity groups, the company said, it is higher than 95 percent for people older than 65, who are at higher risk from the virus than the general population. That certainly is good news.

A second drug developer, Moderna, announced this week its coronaviru­s vaccine is 94.5 percent effective and once final safety and efficacy data is completed in the coming weeks, it will apply for FDA approval.

All this promising news comes with a few caveats. Among the logistics of distributi­ng the vaccines is the challenge that the Pfizer dose must be kept at exceedingl­y low temperatur­es — around minus 94 degrees Fahrenheit, which will require specialize­d refrigerat­ion at individual sites. The Moderna vaccine needs storage at only 36 to 46 degrees.

Both vaccines require two doses, which means the anticipate­d 50 million produced globally by next month would help only half as many people. Still, that’s a welcome start.

Connecticu­t is developing guidelines for how the vaccines should be distribute­d and to whom first. Front line health workers and others most at risk are expected to be the first treated — if all goes well — with the protection not reaching a substantia­l portion of the general population until around April.

For those who might get inoculated in December, the effectiven­ess begins 28 days after the first dose, which means any level of protection wouldn’t happen until early next year.

Though relief is not immediate, the possibilit­y is in sight. Which makes it all the more imperative that people continue to assiduousl­y adhere to common sense practices, such as wearing a face mask in public, using hand sanitizer, washing hands frequently and limiting gatherings to no more than 10 people.

No one wants to be the last person to die before there’s a vaccine.

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