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Determine source of frequent UTIs

- Keith Roach, M.D. Readers may email questions to: ToYourGood­Health@med .cornell.edu or mail questions to 628 Virginia Dr., Orlando, FL 32803.

Dear Dr. Roach: I have a problem with chronic urine infections. I am 78 years old, and suffer often from it. I frequently go to the bathroom five or six times during the night and feel pressure under my stomach. My doctor suggested a biopsy and found blood in my urine, which was later tested for cancer. I was told a week later that I do not have cancer.

My doctor is aware that I cannot take antibiotic­s because I get side effects. He gave me Monurol. I had no aftereffec­ts, but still get recurrence­s of pressure, burning with urination and a burning sensation in my vaginal area. How can

I treat this uncomforta­ble feeling? Must I be on antibiotic­s for the rest of my life?

W.W.

Answer: Recurring symptoms of urine infections can come from either a series of new infections or a single infection that is only partially treated and then comes back. The doctor can settle this by getting several cultures of the urine to see what bacteria are growing. If it’s the same strain each time, that is likely a persistent infection; different organisms indicate recurring new infections.

If it is recurring new infections, the bacteria are having an easy time getting into the bladder. In a 78-year-old woman, lower estrogen levels lead to thinning of the lining of the vagina and vulva — and that includes the lining of the urethra, where urine exits the body. If this lining is thin, bacteria can get into the bladder through the urethra. It is normally treated by vaginal estrogen cream, which is effective.

Persistent infections lead the doctor to suspect an abnormalit­y in the kidney, bladder or ureters, which are the tubes that connect the kidneys with the bladder. A stone is a common source of persistent infection, and it would also explain the blood.

Fosfomycin (Monurol) is a unique antibiotic, not chemically related to others. It is a good choice for urine infections in people with multiple allergies or sensitivit­ies.

But chronic antibiotic use is a last resort. If your doctor hasn’t done a thorough job of investigat­ing the possibilit­ies, I would recommend consultati­on with an expert. A urogynecol­ogist would be the ideal specialist.

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