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UConn to hold ‘unique’ cannabis research symposium

- By Jordan Nathaniel Fenster

Gerald Berkowitz is organizing the state’s firstever academic symposium on cannabis, scheduled for March 16 and 17 at UConn.

Berkowitz is a professor of plant science and landscape architectu­re, but the event will draw researcher­s from a variety of fields, from botany to law and everything in between. UConn, he said, has become something of an epicenter for cannabis research.

“It just so happens that we have scientists who are studying cannabinoi­d receptors in the brain and the central nervous system at UConn Health, and we have scientists in our chemistry department studying the bioavailab­ility of cannabinoi­ds and how you can change their structure to increase uptake,” he said. “We have faculty in pharmacy nursing who are studying THC and pain, as a replacemen­t for opioids.”

The various researcher­s knew that their colleagues were doing related research, but the relationsh­ips were “informal.”

“Just informally, we all got to know each other and started an ad hoc cannabis forum,” Berkowitz said. “So we would give seminars and so on and so forth, and it was clear to me that there was a strong program in cannabis

“Marijuana is a schedule one, right there with heroin. It’s remarkable that we don’t even know what compounds in cannabis might be useful pharmaceut­icals.”

UConn Professor Gerald Berkowitz

stretching from plants to the brain.”

The upcoming event is possible, he said, because legitimate cannabis research is possible for the first time in decades.

“Marijuana is a schedule one, right there with heroin,” he said. That made rigorous academic research into cannabis, how it grows and how it affects the human body, nearly impossible. “It’s remarkable that we don’t even know what compounds in cannabis might be useful pharmaceut­icals.”

Being a so-called “schedule one” drug, Berkowitz explained, means “the federal government says there’s no medical use for it and it’s highly addictive.”

But that, he said, is a hypocrisy. The U.S. Food and Drug Administra­tion has approved use of Epidiolex, a drug derived from CBD, to combat seizures.

The acknowledg­ement by one branch of the federal government that the marijuana plant has benefit for patients with epilepsy, while another branch of the federal government insists the plant has no medical benefits is “absurd,” Berkowitz said.

“It’s kind of absurd for the federal government to say that there’s nothing in marijuana that is pharmaceut­ically useful when the FDA has approved a compound from marijuana that is used to control seizures,” he said.

But with Connecticu­t and other states legalizing cannabis and large companies funding research, Berkowitz agreed we’re in the midst of a golden age of cannabis research, which should rectify the surprising ignorance about a plant used by millions.

“There’s so much that’s not understood about the biochemist­ry of the plant,” he said. “Up until just even three or four years ago, for federal funding agencies like the USDA, even the word ‘hemp’ was no-go. There was no federal support for understand­ing cannabis, understand­ing any potential beneficial effects on humans, understand­ing the plant, and the only people that were doing any research at least on the plant were companies, and they don’t publish their research.”

Berkowitz’s own research involves stimulatin­g the little hairs on the buds, where the chemicals that produce a smell and those that create an effect on the brain are stored. His research has been funded in part by large cannabis companies, but when he visited a facility with a group of students he was told their employees were largely self-taught.

“I took the first UConn class to a medical marijuana growth facility and the owners said to me, ‘We hire people that grow pot in their basements, and those are the experts. There’s no scholarshi­p, there’s no people with horticultu­re degrees that are able to be hired,’” he said. “So I started having undergradu­ate students do research projects and they would just get jobs right off the bat.”

Berkowitz said cannabis conference­s are nothing new. “I get probably 10 emails a day about cannabis conference­s, set up for companies and businesses,” he said, though “none of those is really about research.”

“That’s why the symposium that we’re putting together is absolutely unique,” Berkowitz said. “Because every subject, except the session on policy and law, every speaker is going to be talking about refereed research.”

 ?? Arnold Gold/Hearst Connecticu­t Media file photo ?? Cannabis plants hang in a drying room at the CTPharma cultivatio­n facility in Rocky Hill on Dec. 13.
Arnold Gold/Hearst Connecticu­t Media file photo Cannabis plants hang in a drying room at the CTPharma cultivatio­n facility in Rocky Hill on Dec. 13.

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