Hartford Courant (Sunday)

Should your cocktail carry a cancer warning?

Experts underscore link between alcohol, disease as consumptio­n rises in pandemic

- By Anahad O’Connor

When the pandemic struck last year, many Americans rushed to stock up on alcohol, causing retail sales of wine, beer and liquor to surge across the country.

But the uptick in sales was a worrying sign for health experts focused on cancer prevention. In recent years, a growing number of medical and public health groups have introduced public awareness campaigns warning people to drink with caution, noting that alcohol is the third leading preventabl­e cause of cancer, behind tobacco and obesity.

In October, the American Society for Clinical Oncology (ASCO), which represents many of the nation’s top cancer doctors, along with the American Institute for Cancer Research, the American Public Health Associatio­n and five other groups called on the federal government to add a cancer warning to alcohol labels, saying there was strong scientific consensus that alcohol can cause several types of cancer, including breast and colon cancers. While medical experts have long recognized alcohol as a risk factor for various cancers, including cancers of the mouth, throat, voice box, esophagus and liver, a survey conducted by ASCO in 2017 of 4,016 American adults found that fewer than a third recognized alcohol as a risk factor for cancer.

The European Union, which has some of the highest levels of drinking in the world, announced earlier this year that it planned to slap new health warnings on alcohol and explore new taxes and restrictio­ns on the marketing of alcoholic beverages as part of a $4.8 billion plan to reduce cancer rates. In France, famous for its wine and Champagne, the government announced that it would issue new warnings and policies to discourage heavy drinking as part of a 10-year plan to tackle cancer, the country’s leading cause of death.

The ongoing pandemic underscore­s the urgency of these efforts, as stress, lockdowns and economic uncertaint­y continue to take a toll. In the past year, hospitals across the U.S. have reported an increase in admissions for hepatitis, liver failure and other alcohol-related diseases. A study in the journal Psychiatry Research found that in the first six months of lockdowns, alcohol abuse rose most sharply among people who lost their jobs or who were confined to their homes because of shelterin-place restrictio­ns. The pandemic has also made it easier for people working from home to drink throughout the day without fear of colleagues noticing.

“Workers who would never consider consuming alcohol at the office are now free to drink to excess during work hours while at home,” the study found. “There are grave concerns over the long-term health implicatio­ns of the rising level of alcohol dependence.”

In the U.S., 41% of men and 39% of women will develop cancer at some point in their lifetimes, according to the American Cancer Society. The group estimates that around 42% of newly diagnosed cancers are potentiall­y preventabl­e, by avoiding such measures as cigarette smoking (accounting for some 19% of cancer cases), excess weight (7.8%), drinking alcohol (5.6%), ultraviole­t radiation (5%) and physical inactivity (2.9%). While heavy drinking poses the greatest hazard, moderate drinking — generally defined as two drinks a day for men and one drink a day for women — can also imperil health.

The link between alcohol and cancer was the focus of a recent large study that found that alcohol causes 75,000 new cases of cancer in America every year, as well as 19,000 deaths from the disease. The study, published in January in Cancer Epidemiolo­gy, concluded that alcohol accounted for more than 1 in 8 cases of breast cancer in women and 1 in 10 cases of colorectal and liver cancers nationwide.

“It’s a substantia­l number of cancer cases and cancer deaths that could be prevented,” said Dr. Farhad Islami, senior author of the study and the scientific director of the cancer disparity research team at the American Cancer Society.

Experts say one reason for the lack of awareness is the popular idea that moderate alcohol intake, especially of red wine, is good for heart health, which has drowned out public health messages about alcohol’s impact on cancer risk. But while moderate drinking has long had a health halo, recent studies suggest it may not be beneficial at all. The American Heart Associatio­n states that “no research has establishe­d a cause-and-effect link between drinking alcohol and better heart health,” and that people who drink red wine may have lower rates of heart disease for other reasons, such as healthier lifestyles, better diets or higher socioecono­mic status.

Other analyses have found that moderate drinking can appear to be beneficial in large population studies because the “nondrinker­s” who are used for comparison often include people who don’t drink because they have serious health issues or because they are former heavy drinkers. When studies take these factors into account, the apparent cardiovasc­ular benefits of moderate drinking disappear.

For that reason, the federal government’s Dietary Guidelines for Americans, which once promoted moderate drinking for heart health, no longer makes that claim. The most recent edition of guidelines for the first time included strong language about alcohol and cancer, warning that even moderate drinking can “increase the overall risk of death from various causes, such as from several types of cancer and some forms of cardiovasc­ular disease.”

The American Cancer Society also issued new guidelines last year that for the first time took a tough stance on drinking, warning that for cancer prevention, “there is no safe level of consumptio­n.” Dr. Timothy Naimi, a member of the government’s dietary guidelines advisory committee, said the new recommenda­tions make clear that moderate drinking is not protective and that drinking less is always better than drinking more.

“The new guidelines are very strong in framing alcohol as a leading preventabl­e health hazard,” said Naimi, director of the Canadian Institute for Substance Use Research.

“I think the relationsh­ip between alcohol and a number of the most important cancers is still not widely recognized. But I feel that’s changing.”

 ?? ALFONSO DURAN/FOR THE NEW YORK TIMES ??
ALFONSO DURAN/FOR THE NEW YORK TIMES

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