Houston Chronicle Sunday

UTHealth alumnus gives back to college

Scientist pledges $10.5 million to aid graduate students

- By Jenny Deam

In the world of bio-molecular research, breakthrou­ghs are rare, and fame can be rarer still. Scientist and medical entreprene­ur John Kopchick knows he is lucky to have found both in his lifetime.

So last week he pledged $10.5 million to the University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, his alma mater, to help a new generation get to “Eureka!”

“I spent a wonderful four and a half years here. It’s wonderful coming back,” said Kopchick, 66, who now lives in Athens, Ohio, where he is a distinguis­hed professor of molecular and cellular biology at Ohio University and directs the Growth, Diabetes and Obesity Section of the Edison Biotechnol­ogy Institute.

The announceme­nt of his gift came at a ceremony at the MD Anderson Cancer Center.

The money will fund 15 yearly fellowship­s starting in

2018 to help graduate students pursue their education and research just as Kopchick did nearly four decades before. He earned his Ph.D. in 1980 on a fellowship.

In fact, he and his wife of 41 years, Charlene, were both the first in their families to attend college, which makes the journey all the more remarkable.

“This gift is very studentcen­tric,” he said in an interview before the ceremony, adding that one of the fellowship­s will be set aside for a student with a unique need, be it financial or some other challenge such as a physical disability.

“This is a statement about giving forward, and for me that is important,” said Charlene Kopchick, who is assistant dean of students for campus involvemen­t at Ohio University. “Had John not gotten scholarshi­ps to come here, we wouldn’t be where we are.”

After leaving Houston, Kopchick worked in research for pharmaceut­ical companies before landing at Ohio University. In 1988, while working there, he identified a compound that inhibits the human growth hormone that can lead to a condition called acromegaly, more commonly known as gigantism.

His wife remembers the moment well.

“His excitement was contagious,” she said. “I didn’t know what he was talking about, but I knew it was something big.”

It was as if decidedly unscientif­ic serendipit­y had taken him by the hand.

Working in the pharmaceut­ical industry, he probably had discovered 200 compounds that never once turned into a drug. And then, in a lab in Ohio, he had hit the one that would change his life — and the lives of patients.

But it would not be an easy road. With patent in hand and enthusiasm bursting, he made the rounds looking for a landing for his discovery. He found none.

“I went from elation to depression,” he said. “I was stomping around the world trying to get someone interested.”

Then one day, he was working out at the university and venting his frustratio­n to a football coach who uttered the magic words: “I know a guy.”

That guy turned out to be a former football player, Rick Hawkins, who had found success in the business of clinical trials.

Hawkins remembers looking over Kopchick’s work and thinking: “This is really cool. He’s really got something.”

Together they formed a company and began the uphill climb of getting the drug developed and through the maze of Food and Drug Administra­tion approval. It came in 2005. They sold their company, and the drug is now marketed by Pfizer under the name Somavert.

He has met some of the patients his discovery has helped.

“It’s humbling. It gives me chills,” he said. “The recognitio­n is great, the money is great, but helping a patient is very, very special.”

And even as he passes the baton to the next generation of researcher­s, he is not quite ready to hang up his lab coat.

“We still have some things to do,” he said with a grin.

 ?? UT MD Anderson UTHealth Graduate School of Biomedical Science ?? John Kopchick and his wife, Charlene, donated $10.5 million to the University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences.
UT MD Anderson UTHealth Graduate School of Biomedical Science John Kopchick and his wife, Charlene, donated $10.5 million to the University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences.

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