Search for coronavirus vaccine has become a global sprint
WASHINGTON — A global arms race for a coronavirus vaccine is underway.
In the three months since the virus began its deadly spread, China, Europe and the United States all have set off at a sprint to become the first to produce a vaccine. But while there is cooperation on many levels — including among companies that are ordinarily fierce competitors — hanging over the effort is the shadow of a nationalistic approach that could give the winner the chance to favor its own population and potentially gain the upper hand in dealing with the economic and geostrategic fallout from the crisis.
Any new vaccine that proves potent against the coronavirus — clinical trials are underway in the United States, China and Europe already — is sure to be in short supply as governments try to ensure that their own people are the first in line.
In China, 1,000 scientists are at work on a vaccine. Researchers affiliated with the Academy of Military Medical Sciences have developed what is considered the nation’s front-runner candidate for success and is recruiting volunteers for clinical trials.
China “will not be slower than other countries,” Wang
Junzhi, a biological products quality control expert with the Chinese Academy of Sciences, said Tuesday at a news conference in Beijing.
President Donald Trump has talked in meetings with pharmaceutical executives about making sure a vaccine is produced on American soil to assure the U.S. controls its supplies. German government officials said they believed he tried to lure a German company, CureVac, to do its research and production, if it comes to that, in the United States.
The company has denied it received a takeover offer, but its lead investor made clear there was some kind of approach.
Asked by the German magazine Sport 1 about how the contact with Trump had unfolded, Dietmar Hopp, whose Dievini Hopp BioTech Holding owns 80 percent of the company, said: “I personally didn’t speak to Mr. Trump. He spoke to the company and they immediately told me about it and asked what I thought of it, and I knew immediately that it was out of the question.”
The report of the approach was enough to prompt the European Commission to pledge another $85 million to the firm, which has already had support from a European vaccine consortium.
The same day, a Chinese company offered $133.3 million for an equity stake and other consideration from another German firm in the vaccine race, BioNTech.
“There has been a global wake-up call that biotechnology is a strategic industry for our societies,” Friedrich von Bohlen, the managing director of the holding company that owns 82 percent of CureVac.
After two decades of farming out drug production to China and India, “you want the whole production process close to home,” von Bohlen said.
Some experts view the geopolitical competition as healthy, as long as any successes are shared with the world — which government officials routinely assure they will be.
But they do not say how, or more important, when. And many analysts recall what happened during the swine flu epidemic in 2009, when a company in Australia that was among the first to develop a single-dose vaccine was required to satisfy demand in Australia before fulfilling export orders to the United States and elsewhere.
That spurred outrage, conspiracy theories and congressional hearings into the reasons for the shortfall.
“You want everybody to cooperate, everybody to race as quickly as they can to a vaccine and the best candidates to move forward,” said Dr. Amesh Adalja of the Center for Health Security at Johns Hopkins University.
But if those showing signs of success are wondering if their companies will be nationalized, he said, it creates a complication that “you don’t want to have when you are trying to get a vaccine made as quickly as possible.”
Executives of the world’s leading pharmaceutical companies said Thursday that they were working together and with governments to assure that a vaccine is developed as quickly as possible and distributed equitably. But they implored governments not to hoard a vaccine once it is developed, saying that to do so would be devastating for the broader goal of stamping out the coronavirus pandemic.
“I would encourage everyone not to get into this trap of saying we have to get everything into our countries now and close the borders,” said Severin Schwan, the chief executive of the Swiss pharmaceutical company Roche. “It would be completely wrong to fall into nationalist behavior that would actually disrupt supply chains and be detrimental to people around the world.”
Adding to the pressure is Trump’s near-daily assurance that breakthroughs are on the way. While antiviral drugs to treat the effects of the coronavirus may be tested under “compassionate use” guidelines that allow experimentation on desperately ill patients, a vaccine remains at least 12-18 months away, U.S. officials and the leaders of major pharmaceutical companies say.
“Vaccines are injected into healthy people, so we need to ensure safety,” a process that takes time, David Loew, an executive vice president of Sanofi Pasteur of France, said Thursday.