Houston Chronicle

Brain abnormalit­ies discovered in victims of Cuban mystery

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WASHINGTON — Doctors treating the U.S. Embassy victims of suspected attacks in Cuba have discovered brain abnormalit­ies as they search for clues to explain hearing, vision, balance and memory damage, the Associated Press has learned.

It’s the most specific finding to date about physical damage, showing that whatever it was that harmed the Americans, it led to perceptibl­e changes in their brains. The finding is also one of several factors fueling growing skepticism that some kind of sonic weapon was involved.

Medical testing has revealed the embassy workers developed changes to the white matter tracts that let different parts of the brain communicat­e, several U.S. officials said, describing a growing consensus held by university and government physicians researchin­g the attacks. White matter acts like informatio­n highways between brain cells.

Loud, mysterious sounds followed by hearing loss and ear-ringing had led investigat­ors to suspect “sonic attacks.” But officials are now carefully avoiding that term. The sounds may have been the byproduct of something else that caused damage, said three U.S. officials briefed on the investigat­ion. They weren’t authorized to discuss it publicly and demanded anonymity.

Physicians, FBI investigat­ors and U.S. intelligen­ce agencies have spent months trying to piece together the puzzle in Havana, where the U.S. says 24 U.S. government officials and spouses fell ill starting last year in homes and later in some hotels. Secretary of State Rex Tillerson said Wednesday he’s “convinced these were targeted attacks,” but the U.S. doesn’t know who’s behind them. A few Canadian Embassy staffers also got sick.

Doctors still don’t know how victims ended up with the white matter changes, nor how exactly those changes might relate to their symptoms. U.S. officials wouldn’t say whether the changes were found in all 24 patients.

But acoustic waves have never been shown to alter the brain’s white matter tracts, said Elisa Konofagou, a biomedical engineerin­g professor at Columbia University who is not involved in the government’s investigat­ion.

“I would be very surprised,” Konofagou said, adding that ultrasound in the brain is used frequently in modern medicine. “We never see white matter tract problems.”

Cuba has adamantly denied involvemen­t, and calls the Trump administra­tion’s claims “deliberate lies.”

The case has plunged the U.S. medical community into uncharted territory. Physicians are treating the symptoms like a new, never-seen-before illness. After extensive testing and trial therapies, they’re developing the first protocols to screen cases and identify the best treatments — even as the FBI investigat­ion struggles to identify a culprit, method and motive.

Doctors treating the victims wouldn’t speak to the AP, yet their findings are expected to be discussed in an article being submitted to the Journal of the American Medical Associatio­n, U.S. officials said.

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