Houston Chronicle

Birth defects on rise in areas of Zika virus

Portion of South Texas among parts of U.S. that have seen a big spike in abnormalit­ies

- By Daniel Chang

The kinds of birth defects associated with the Zika virus have increased in parts of the U.S. where mosquitoes were spreading the virus in 2016.

MIAMI — The kinds of birth defects associated with Zika, including microcepha­ly and other brain abnormalit­ies, have increased in parts of the United States where mosquitoes were spreading the virus in 2016, according to a new report from the federal Centers for Disease Control and Prevention.

Areas with local spread of Zika — including South Florida, a portion of South Texas, and Puerto Rico — saw a 21 percent spike in these kinds of birth defects during the second half of 2016 compared with births that took place during the first half of that year, CDC officials reported.

However, researcher­s said they do not know if the increase is due to local spread of Zika or other factors because most mothers who delivered babies with birth defects associated with the virus did not have laboratory evidence of infection. Those mothers either were never tested, were not tested at the right time, or were not exposed to Zika, CDC officials said.

Researcher­s analyzed nearly 1 million births from 2016 in 15 states and territorie­s as part of the report, which provided the first comprehens­ive data on the prevalence of birth defects potentiall­y linked to Zika.

They identified 2,962 babies and fetuses with birth defects potentiall­y related to Zika, including 1,456 with brain abnormalit­ies or microcepha­ly — which causes abnormally small heads and incomplete brain developmen­t. There was no state breakdown.

An additional 581 had neural tube defects, 262 had eye abnormalit­ies and 662 had some other form of central nervous system dysfunctio­n.

Among the nearly 3,000 birth defects identified, though, a total of 2,821 cases either never received Zika testing or their results were not available for the report.

Because the increase in birth defects was detected during the second half of 2016, CDC researcher­s said more surveillan­ce is necessary to capture births from 2017, when many pregnant mothers affected by Zika would have delivered their babies.

Zika is spread primarily by the bite of an infected mosquito, most commonly the Aedes aegypti species, but the virus can also be transmitte­d by sex and through blood transfusio­ns.

Pregnant women are considered to be at the greatest risk from Zika because the virus has been shown to cause microcepha­ly and other neurologic­al disorders in children born to mothers infected while pregnant.

In 2016, the CDC and Florida Department of Health identified Miami’s Wynwood neighborho­od as the first area in the continenta­l United States with local spread of Zika by mosquitoes, triggering a travel advisory that warned pregnant women to avoid travel to Miami. Local spread of the virus also cropped up in areas of Miami Beach and Miami’s Little River neighborho­od.

That year, a total of 299 pregnant women in Florida were reported to have laboratory­confirmed Zika, and four babies were born with congenital Zika syndrome, according to the state’s surveillan­ce data.

A total of 1,469 Zika infections, most acquired by people traveling outside the country, were reported in Florida in 2016.

Zika waned in 2017, with 249 cases statewide, including 127 pregnant women and three babies born with congenital Zika syndrome.

 ?? Katie Falkenberg / Los Angeles Times ?? Maria da Luz Mendes Santos holds her daughter, Heloyse, who was born with microcepha­ly. Researcher­s identified 2,962 babies and fetuses with birth defects potentiall­y linked to Zika in 2016.
Katie Falkenberg / Los Angeles Times Maria da Luz Mendes Santos holds her daughter, Heloyse, who was born with microcepha­ly. Researcher­s identified 2,962 babies and fetuses with birth defects potentiall­y linked to Zika in 2016.

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