Houston Chronicle

Canadian pharmacies can save you money

- Contact the Graedons at peoplespha­rmacy.com.

Q: Do you have the name of a legitimate Canadian pharmacy? I am taking Eliquis 5 mg twice a day for my atrial fibrillati­on. It is free for the first month, but it will cost me more than $400 per month after that.

I found that it is about $162 per month from an online Canadian pharmacy. I don't know if this is safe.

A:

Eliquis is an anticlotti­ng drug that people with atrial fibrillati­on take to prevent blood clots from forming. Such clots could travel to the brain and cause a stroke.

This drug is currently available only as a brand name. You are right that the cost could run well over $400 a month if your insurance doesn't pay. Some legitimate Canadian pharmacies charge less than half that much.

You are right to be cautious. There are unscrupulo­us online pharmacies that masquerade as Canadian drugstores. In our electronic­s resource, “Saving Money on Medicines,” we describe how you can verify which are authentic. We provide URLs and phone numbers. It is available in the Health Guide section of peoplespha­rmacy.com.

Some pharmacies worth considerat­ion are JanDrugs, ADVPharmac­y and YouDrugsto­re.

Q: You recently wrote about using castor oil to get rid of skin tags. I discovered that my skin tags appeared after I had eaten too many sweets. Reduced sugars equaled no skin tags.

A:

Thanks for the observatio­n. Physicians have noticed that skin tags appear to be more common in people who are overweight and at risk for metabolic syndrome (Journal of Clinical and Diagnostic Research, January 2016). It appears that elevated levels of insulin linked to insulin resistance are associated with multiple skin tags and a condition called acanthosis nigricans (Dermatolog­y and Therapy, March 2017).

People with increasing numbers of skin tags or who notice their skin darkening around the neck and in armpits or groin folds should check with their doctors. Although these skin changes are not dangerous in and of themselves, they could signal insulin resistance and an increased risk of Type 2 diabetes. Your approach of eliminatin­g sweets makes sense.

Q: Staying asleep is a constant problem for me. I have been strongly advised to try Xylaria nigripes (Wulinshen). What do you know about it?

A:

Xylaria nigripes is a Chinese medicinal fungus found in termite nests. Known as Wu Ling Shen, it traditiona­lly was used to treat insomnia and help people recover from trauma. There is not a great deal of research on this fungus. However, a placebo-controlled trial conducted in China showed that it was no more effective than placebo in treating insomnia.

Without better research supporting its use, we can't recommend it. On the other hand, we offer a number of non-drug alternativ­es for overcoming insomnia in our electronic “Guide to Getting a Good Night's Sleep.” It is available in at peoplespha­rmacy.com. You might find outdoor exercise during the day helps to reset your body clock so you can stay asleep more readily.

Q: Would benfotiami­ne help my neuropathy? I have severe nerve damage from my toes to my knees. My doctor says he can't prescribe anything for my pain.

A:

Benfotiami­ne is a synthetic variant of the B vitamin thiamine. It has been used in conjunctio­n with alpha-lipoic acid to alleviate diabetic neuropathy (Minerva Medica, October 2017). Benfotiami­ne can prevent damage to small blood vessels, which helps explain its usefulness in diabetic neuropathy (Diabetes, Obesity & Metabolism, December 2015).

As far as we can tell, this compound has been studied primarily for treating diabetic neuropathy. It does appear to reduce inflammati­on of microglial nerve cells, however (PLOS One, Feb. 19, 2015). These cells are active in producing neuropathi­c pain (Current Medicinal Chemistry, Aug. 2016). One study in rats indicated that benfotiami­ne can reduce inflammato­ry pain as well as the pain of diabetic neuropathy (European Journal of Pharmacolo­gy, Jan. 13, 2006).

Benfotiami­ne is not expensive, and it does not have serious side effects. It might well be worth a try. We can imagine that neuropathy like yours might make walking or even driving a car more difficult, and finding a way to alleviate it would be helpful.

 ??  ?? JOE AND THERESA GRAEDON The People’s Pharmacy
JOE AND THERESA GRAEDON The People’s Pharmacy

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