Houston Chronicle

Pets, their owners gain from research

- By Matthew Bailey Bailey is president of the nonprofit Foundation for Biomedical Research in Washington, D.C.

A Colorado State University scientist is testing a groundbrea­king vaccine that could prevent cancer in dogs.

About 800 dog owners have volunteere­d their healthy canine companions for a clinical trial led by the director of clinical research at CSU's Flint Animal Cancer Center. The pets will receive either the vaccine or a placebo and will undergo regular checkups to monitor for tumors. Researcher­s have spent more than a decade developing the drug. They are hopeful that it could stave off every form of cancer.

Six million canines are diagnosed with cancer every year. If the vaccine works, it could save tens of millions from an untimely end. And since dogs and humans develop similar cancers, researcher­s are optimistic the vaccine could ultimately be used in people.

Eradicatin­g cancer with a single shot sounds like science fiction. But thanks to research in animal models, it could soon be scientific fact. Impeding this research, as some socalled animal rights activists would have us do, would be a disaster for pets and people alike.

Americans love their pets. More than 60 million U.S. households have a dog; 47 million have a cat.

Our pets rely on medicines that were developed thanks to humane research in animal models. Several vaccines can prevent cats from developing feline leukemia virus, which kills 85 percent of cats within three years of diagnosis. New antiinflam­matory drugs can enable dogs with arthritis, which afflicts 1 in 5 dogs, to move with less pain. Cats with diabetes — about 1 in 200 — now have insulin treatments to manage their condition.

Without clinical trials in pets, none of these advances would have been possible.

Many animal researcher­s are pet owners who chose their profession specifical­ly to help their furry friends. Consider Dr. Jessica Quimby of Colorado State University. In a profile on the school's website, she explained how she developed an affection for barn cats as a girl growing up in Wisconsin. Now, she's uncovering ways to help felines who have kidney disease, which afflicts about 10 percent of cats over 10 years old. Quimby has spent the past decade analyzing how an antidepres­sant for humans might help cats with failing kidneys boost their appetites and live longer, healthier lives.

There are many more potential treatments for animals with dangerous diseases on the horizon.

Researcher­s at CSU's James L. Voss Veterinary Teaching Hospital are attempting to find the first definitive non-invasive diagnostic test for feline infectious peritoniti­s, a highly fatal disease that kills kittens without any warning symptoms. Other CSU veterinari­ans are testing how a compound derived from marijuana can treat epilepsy in dogs without the side effects of debilitati­ng sedatives.

Scientists at the University of Illinois are starting studies for a potential treatment for oral squamous cell carcinoma, which is the most prevalent oral cancer in cats.

Such studies can also help humans. A new report published in the Proceeding­s of the National Academy of Sciences, for example, has revealed that medicines used to protect pets from fleas and ticks could actually help humans fight Zika and malaria.

Meanwhile, research from Texas A&M University on brain tumors in dogs, for example, could soon yield insight into human brain tumors. Back in 2013, the FDA sped up its approval of a drug for lymphoma after it helped dogs.

Despite its impressive history of producing cures for all sorts of diseases that afflict both pets and humans, animal research has its critics. They claim that these trials are unnecessar­y.

Nothing could be further from the truth. Animal research has already saved, and will continue to save, millions of pets' lives. Without animal research, how many of our cats would be dying prematurel­y of leukemia? Or how many of our dogs would be unable to run and play because of debilitati­ng arthritic pain?

Cats and dogs are treasured family members for millions of Americans. To ensure that their furry friends can live long, happy lives, pet lovers must support animal testing.

Americans love their pets. More than 60 million U.S. households have a dog; 47 million have a cat.

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