Houston Chronicle

Fighting Texas’ own opioid epidemic

- By F. Leland McClure III

As someone who has studied use and misuse of prescripti­on opioids and other drugs for much of my career, I know drug misuse can happen to anyone. I have had friends, relatives and neighbors pulled into misuse, which includes substance-use disorders and other dangerous behaviors, such as drug combining.

And I am not alone. A recently released statewide poll found that 1 of 3 adults in Texas knows someone who has been addicted to prescripti­on painkiller­s.

As a Texas native, I’m especially dismayed by a recent report showing the number of people in Texas who died from opioid overdoses climbed 4.1 percent — nearly 3,000 deaths — over just the last year.

This tragic loss of lives is unacceptab­le. And preventabl­e.

Addressing the opioid drug problem in Texas and other states requires a comprehens­ive and aggressive approach. I applaud Texas on what it has done to date to address this problem. While strategies to increase medication-assisted treatment programs and limiting overprescr­ibing of opioids for transient pain are worthwhile goals, too often these measures focus on the extremes of the problem, including individual­s already grappling with substance-use disorders or those for whom an opioid prescripti­on is given for transient pain.

Based on what I’ve seen, many of the individual­s most at risk are those who do not yet have a substance-use disorder but could develop one. And there are those who practice other dangerous forms of drug misuse. These individual­s are often victims of daily chronic pain for which longterm use of prescripti­on opioids is the best source of relief.

The problem is that physicians may believe that they can tell without definitive evidence if a patient will misuse a prescribed therapy. Misuse includes supplement­ing, substituti­ng or abstaining from taking their prescripti­ons. However, these assumption­s are often wrong.

For example, insights from a 2018 analysis of more than 3.9 million de-identified aggregated drug monitoring tests reveal a startling truth: more than half of patients who take prescripti­on opioids, amphetamin­es and other therapies show signs of misuse when tested. Forms of misuse include dangerous drug combinatio­ns with other drugs like fentanyl, a powerful opioid, and benzodiaze­pines, a widely used class of anti-anxiety medication­s. Use of illicit drugs, such as heroin, is also a growing national problem.

Several organizati­ons, including the Centers for Disease Control and Prevention, Department of Veterans Affairs, and the American Pain Society, already recognize the value of physicians working with their patients to monitor appropriat­e and safe use of prescripti­on medication­s including opioids. But more is needed.

Physicians who monitor prescripti­on drug use can play an important role in identifyin­g statewide misuse trends. Their efforts complement Prescripti­on Drug Monitoring Programs, which are state-based databases that track prescripti­on data to help reveal possible concerns. These programs, such as the “Texas Prescripti­on Monitoring Program,” are necessary and useful to help curtail prescripti­on and illicit drug misuse.

An objective, real-time snapshot of medication adherence helps patients and physicians discuss a treatment plan, prescripti­ons the patient may be taking, and the benefits and risks associated with pain medication­s. It takes guesswork out of clinical care and provides transparen­cy between patients and physicians to ensure that patients are receiving the best and safest treatment possible.

Texas’ state leaders can make it easier for physicians to keep patients safe by adopting regulation­s and policies, such as the CDC Guidelines for Prescribin­g Opioids for Chronic Pain, that support the use of drug testing before commencing opioid therapy and, at least annually thereafter, to assess for prescribed medication­s, other controlled prescripti­on drugs and illicit substances.

For many Texans, pain is a very real, daily challenge, and physicians must be allowed to consider opioids for relief when other measures won’t do. For these patients, drug monitoring can aid the delivery of appropriat­e care while reducing risks. If physicians do not have access to all viable means to protect these patients, it is all but certain that prescripti­on drug misuse — and drug overdose deaths — will continue.

McClure is the director of medical affairs for Quest Diagnostic­s, the world’s leading provider of diagnostic­s informatio­n services, including in clinical drug monitoring.

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