Houston Chronicle

Solugen’s sweet spot in hydrogen peroxide

Compound’s use in hydraulic fracturing makes it a popular substance in Texas

- By Andrea Leinfelder STAFF WRITER

Gaurab Chakrabart­i was studying cancer cells in 2013 when he discovered a protein that turns sugar, water and oxygen into hydrogen peroxide — a surprising­ly versatile (and lucrative) chemical.

His initial focus was understand­ing how cancer cells make hydrogen peroxide to mutate their DNA and survive attacks from the body’s immune system. But upon discoverin­g the protein, Chakrabart­i recognized the chemical’s positive uses. It prevents infection on a scraped knee, cleans up grease, helps etch printed circuit boards and kills bacteria on fruits and vegetables.

Its ability to clean wastewater from hydraulic fracturing could be the most popular use in Texas, a propositio­n that has helped Houston-based Solugen raise nearly $20 million from investors in Silicon Valley.

“What if you could use that water for other things?” Chakrabart­i said.

Solugen creates hydrogen peroxide by placing natural materials — sugar, water, oxygen and a proprietar­y catalyst derived from the protein — into a reactor system. The system does not require the high pressure or intense heat typical of making the chemical compound.

And by building a portable reactor system that’s 23 feet tall and mounted on a semi-trailer truck, Solugen could help companies make hydrogen peroxide on their job sites. They would no longer pay to ship it across the country.

“If you look at the chemicals market, in a large nutshell, it’s really constraine­d by logistics and shipping,” he said.

Chakrabart­i became interested in hydrogen peroxide while earning his Ph.D. in biochemist­ry and M.D. training in oncology at the University of Texas Southweste­rn Medical Center in Dallas. His friend and cofounder Sean Hunt was scrutinizi­ng the more traditiona­l method for making hydrogen peroxide while earning his Ph.D. in chemical engineerin­g at the Massachuse­tts Institute of Technology.

Long-distance partners

They teamed up and started Solugen in early 2016. Still at school, Chakrabart­i worked from his kitchen in Dallas and Hunt worked from his apartment in Cambridge.

The company became a full-time endeavor after graduation, and their first round of funding came in May 2016 when Solugen won $10,000 at an MIT business competitio­n. That was enough money to lease a sliver of warehouse space in Dallas, buy PVC pipe from Home Depot and order used pumps from eBay. The first reactor system cost $7,000 to make.

Orders trickled in as the company pitched its product to semiconduc­tor manufactur­ers. Then word got out among the float spas, where people get into pods filled with Epsom salts and water to float in silence and darkness. The spas use hydrogen peroxide to clean the water, and Solugen was quickly overwhelme­d with orders.

“We literally slept on the floor of the warehouse because we had to operate this thing continuous­ly,” Chakrabart­i said.

But those spas turned the company’s initial $10,000 investment into monthly revenue of $12,000 to $14,000. It also helped Solugen get accepted into the Y Combinator accelerato­r program in Silicon Valley, where Chakrabart­i and Hunt spent the first three months of 2017.

“Y Combinator shifted our thinking,” Chakrabart­i said, “into how do we create a minimum viable product that gets the customer excited enough to take out their checkbook.”

They received $5 million in seed financing from Y Combinator and others, and they used the money to launch a consumer cleaning product called Ode to Clean.

‘Trojan horse’

From the start, these wipes were intended as a steppingst­one to something grander. A plan that needed Houston’s petrochemi­cal workforce. So the company returned to Texas and leased a warehouse in Bellaire, where it produced the hydrogen peroxide cleaning portion of the wipes. The liquid was then sent to a company that turned plant materials into disposable wipes, and that company manufactur­ed the end product.

“We wanted to use this as a Trojan horse to go into these bigger companies who wouldn’t even look at us before,” Chakrabart­i said.

The plan worked. Roughly six months after its launch, Ode to Clean was acquired by wet wipe manufactur­er Diamond Wipes Internatio­nal in a deal Chakrabart­i said was worth tens of millions of dollars. This included a contract where Solugen would continue supplying the company with hydrogen peroxide.

The wipes caught the attention of venture capitalist­s, too, who invested $14 million in a Series A round that closed November 2018.

But the main draw was Solugen’s potential to disrupt the chemical market. In addition to hydrogen peroxide, the company’s catalyst could be used to make peracetic acid, polymers used in plastics and other chemicals.

“The petrochemi­cal industry hasn’t seen fundamenta­l innovation since the age of the polymers,” said Seth Bannon, founding partner at San Franciscob­ased venture capital firm Fifty Years. “The entire industry is somewhat stagnant and, on top of that, it’s incredibly environmen­tally destructiv­e.”

One in five of his firm’s portfolio companies are headquarte­red outside of Silicon Valley. Yet Fifty Years has invested more than $8 million into Solugen. Bannon said he would have supported Solugen’s team from almost anywhere, praising their speed as “exceptiona­lly fast, even compared to companies that are just making software.” But he thinks Houston is a good location for attracting petrochemi­cal talent that could help them scale.

Solugen has 24 workers, including Chakrabart­i and Hunt, and plans to double that within the next year.

Expansion in 2020

It produces 120 tons of hydrogen peroxide a year, about 300 gallons a day, but is investing in a facility near Stafford that could produce 50 times that. The $10 million project is expected to open in early 2020.

And for a poetic note to this entreprene­urial tale, Chakrabart­i said the new location was previously occupied by a chemical manufactur­er that used fossil fuels as feedstock. Solugen has knocked down its building and its old-school way of thinking and will build a biobased chemicals plant.

 ?? Photos by Steve Gonzales / Staff photograph­er ?? Gaurab Chakrabart­i, left, is a co-founder and CEO of Solugen. Sean Hunt, right, is a co-founder and chief technology officer for the company formed in 2016.
Photos by Steve Gonzales / Staff photograph­er Gaurab Chakrabart­i, left, is a co-founder and CEO of Solugen. Sean Hunt, right, is a co-founder and chief technology officer for the company formed in 2016.
 ?? Steve Gonzales / Staff photograph­er ?? Solugen has 24 employees and plans to double that number within the next year.
Steve Gonzales / Staff photograph­er Solugen has 24 employees and plans to double that number within the next year.

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