Houston Chronicle

Fish oil is finally getting some respect

- JOE AND TERESA GRAEDON Contact the Graedons at peoplespha­rmacy.com.

Q: I’ve taken fish oil successful­ly for years for lupus, osteoarthr­itis, dry eye and cardiovasc­ular benefits. Three different specialist­s recommende­d it. Even if they changed their minds about it tomorrow, their updated opinion wouldn’t alter my opinion on the benefits of fish oil.

I’ve found that quality matters for fish oil, as it does in many things in life. The amount and ratio of EPA and DHA are also important.

A: A recent review of three large randomized controlled trials concluded that marine omega-3 fats (fish oil) can reduce the risk of cardiac complicati­ons and death from cardiovasc­ular causes (Mayo Clinic Proceeding­s, online, Oct. 15, 2019). One of these trials (REDUCE-IT) used a prescripti­on pharmaceut­ical EPA product, Vascepa.

A different meta-analysis published in the Journal of the American Heart Associatio­n (Oct. 1, 2019) also concluded that fish oil supplement­s can reduce the risk of heart attacks and death from cardiovasc­ular disease. In addition, there is evidence that omega-3 fats have potential in treating autoimmune diseases like yours (Frontiers in Immunology, Sept. 27, 2019).

Q: I have been on clonazepam, amitriptyl­ine, levothyrox­ine, atorvastat­in, atenolol and warfarin since 1994. Last Christmas, I received my first generics from Indian manufactur­ers. This has been a nightmare, so I now buy brand-name Klonopin and attempt to get as many of my drugs as possible from Canada.

Too many generic drugs are not working because the Food and Drug Administra­tion cannot monitor all offshore Indian and Chinese manufactur­ers. I have had credible sources tell me that drug companies overseas check flight manifests to see when American FDA inspectors are coming.

Please send letters to the FDA to try to effect change. Bring drug manufactur­ing back to the U.S. where the agency can monitor it properly!

A: You will be very interested in Katherine Eban’s new book, “Bottle of Lies: The Inside Story of the Generic Drug Boom.” She covers the FDA’s ineffectua­l struggles to oversee generic drug manufactur­ing outside the country, especially in India and China.

Others may wish to know how to buy medication­s from Canada. Brand-name drugs are frequently much more affordable at reputable Canadian pharmacies.

To learn more about how to distinguis­h legitimate Canadian online pharmacies from counterfei­t operations, you may wish to read our eGuide to Saving Money on Medicines. You can find this electronic resource at PeoplesPha­rmacy.com in our Health eGuides section. Q: Recently my wife had revision hip surgery. The orthopedic surgeon prescribed a single 325-mg aspirin tablet a day.

In a previous episode, she was prescribed Lovenox, an injectable blood-clot preventive. The Lovenox cost $750, whereas the aspirin was just pocket change. Maybe doctors are starting to move away from high-cost drugs.

A: After joint-replacemen­t surgery, doctors often prescribe an anticoagul­ant to prevent life-threatenin­g blood clots. A study in JAMA Surgery ( January 2019) demonstrat­ed that aspirin was comparable to far more expensive anticoagul­ants.

A new study in Orthopedic Surgery (October 2019) compared aspirin to rivaroxaba­n (Xarelto) after hip-fracture surgery. The surgeons concluded that “Aspirin may be an effective, safe, convenient and cheap alternativ­e for extended prophylaxi­s after hip-fracture surgery.”

 ?? Fotolia ?? The omega-3 fats in fish oil have been shown to reduce the risk of cardiac complicati­ons.
Fotolia The omega-3 fats in fish oil have been shown to reduce the risk of cardiac complicati­ons.
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