Houston Chronicle

A forecast estimates the U.S. death toll could hit 410,000 by year’s end.

- By Joel Achenbach and William Wan

The global death toll from the coronaviru­s pandemic could triple by year’s end, with an additional 1.9 million deaths, while a fall wave of infections could drive fatalities in the United States to 410,000, according to a new forecast from the Institute for Health Metrics and Evaluation at the University of Washington.

The estimate reinforces warnings by many experts that cooler, drier weather and increased time spent indoors could boost viral transmissi­on in the Northern Hemisphere surge this fall and winter — something typically seen with other respirator­y viruses.

The institute’s forecasts were influentia­l earlier in the pandemic in guiding policies developed by the White House coronaviru­s task force, but they have been criticized by some experts as projecting further into the future than can be done reliably.

The U.S. death toll from COVID-19 now stands at over 187,000, according to Johns Hopkins University. The IHME model projects that under the most likely scenario, 410,451 people in the United States will have died by Jan. 1.

The best-case scenario is 288,381 deaths and worst-case is 620,029, that model forecasts.

The scenarios pivot on human behavior and public policy. The best-case scenario would result from near-universal mask-wearing and the maintenanc­e of social distancing and government mandates limiting the size of indoor gatherings. The worst-case scenario assumes that people and their communitie­s stop taking precaution­s.

“It’s easy given the summer lull to think the epidemic is going away,” Christophe­r Murray, director of IHME, said Friday on a conference call. But there are “bleak times ahead in the Northern Hemisphere winter, and unfortunat­ely we are not collective­ly doing everything we can to learn from the last five months.”

In recent weeks, the daily numbers of U.S. infections and deaths have gradually tapered, following an early summer surge driven largely by community transmissi­on in the Sun Belt. But experts warn that viral infections typically spike in the weeks after school resumes and when colder, drier weather can help viruses stay viable longer and spread more easily.

One key insight in recent months is that the coronaviru­s has a much harder time transmitti­ng outdoors. But as temperatur­es drop, people will spend more time inside.

Few models forecast as far into the future as IHME does. Many do not project further than four to six weeks ahead.

“Beyond that, it’s all conjecture and guesswork because there are so many factors we just can’t predict and factors about transmissi­on that truthfully scientists don’t understand very well yet,” said Jeffrey Shaman, an infectious-disease expert who leads the modeling team at Columbia University. “What happens the next few months really depends on what we do as a society the next few weeks.”

Murray defended the longerrang­e projection­s, however, saying they are intended to help government leaders and the public make decisions now to avoid the worstcase scenario.

The new forecasts represent the institute’s first attempt to model the global spread of the virus and show the daily death toll peaking in mid-December at about 30,000, a more than fivefold increase from the current daily fatality numbers.

The specific timing of the second wave matters less, he said, than the fact that it is likely to happen and that many deaths could be avoided if precaution­s are taken now. The IHME projects that with rigid adherence to social distancing and mask-wearing, 770,000 lives could be saved globally by year’s end.

One of the most useful tools for public health officials following different projection­s has been “ensemble models” — an aggregatio­n of several of the country’s leading models to make a more reliable forecast. One of the most heavily used ensemble models — assembled by Nicholas Reich, a biostatist­ician at the University of Massachuse­tts — shows deaths declining slightly but maintainin­g a fairly high rate of more than 5,000 a week for the next four weeks, with a likely total of 205,093 before the end of September.

But the recent declines in cases and deaths appear to be prompting a relaxation in behavior that could quickly drive those numbers back up. One model that takes into account the extent of social distancing, using cellphone data, forecasts the daily number of deaths increasing over the course of this month from roughly 1,000 a day to almost 2,000 by the end of September.

“We’ve been seeing mobility increase the last few weeks,” said Lauren Ancel Meyers of the University of Texas at Austin, who developed the model that factors in mobility.

In Texas, mobility data shows more people staying home in June when hospitaliz­ations were going up at alarming rates. But since August, that mobility has accelerate­d.

“One of the challenges is as soon as things look good in the community, it’s tempting to say the virus is gone,” Meyers said. “What we really should be thinking is: How did we get to this better place? By being cautious and vigilant. And instead of relaxing, we should focus on the things that worked.”

 ?? Mike Stocker / Tribune News Service ?? Infectious disease experts are urging continued use of safety measures, including face masks and social distancing, as fall and winter get underway. Signs along the boardwalk remind beach visitors Wednesday in Hollywood, Fla.
Mike Stocker / Tribune News Service Infectious disease experts are urging continued use of safety measures, including face masks and social distancing, as fall and winter get underway. Signs along the boardwalk remind beach visitors Wednesday in Hollywood, Fla.
 ?? Frederic J. Brown / AFP via Getty Images ?? Los Angeles testing sites are closing for the Labor Day weekend due to extreme heat. As more people stay indoors during the winter, officials warn that cases could skyrocket.
Frederic J. Brown / AFP via Getty Images Los Angeles testing sites are closing for the Labor Day weekend due to extreme heat. As more people stay indoors during the winter, officials warn that cases could skyrocket.

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