BRIEF SUMMARY OF PATIENT INFORMATION AIMOVIG® (AIM-oh-vig) (erenumab-aooe) injection, for subcutaneous use

What is AIMOVIG?

• AIMOVIG is a prescription medicine used for the preventive treatment of migraine in adults. It is not known if AIMOVIG is safe and effective in children under 18 years of age.

Who should not use AIMOVIG?

• Do not use AIMOVIG if you are allergic to erenumabaooe or any of the ingredients in AIMOVIG. See the end of this Patient Information for a complete list of ingredients in AIMOVIG.

Before you start using AIMOVIG, tell your healthcare provider about all your medical conditions, including if you are:

• Allergic to rubber or latex. The needle shield within the white or orange cap of the single-dose prefilled SureClick® autoinjectors and the gray needle cap of the single-dose prefilled syringes contain dry natural rubber.

• Pregnant or plan to become pregnant. It is not known if AIMOVIG will harm your unborn baby.

• Breastfeeding or plan to breastfeed. It is not known if AIMOVIG passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while using AIMOVIG.

Tell your pharmacist or healthcare provider about all the medicines you take, including any prescription and overthe-counter medicines, vitamins, or herbal supplements.

How should I take AIMOVIG?

• See the detailed “Instructions for Use” on complete information on how to take AIMOVIG.

• Take AIMOVIG exactly as your healthcare provider tells you to take it.

• Before you inject, always check the label of your singledose prefilled autoinjector or single-dose prefilled syringe to make sure you have the correct medicine and the correct dose of AIMOVIG.

• AIMOVIG is injected under your skin (subcutaneously) 1 time each month.

• AIMOVIG comes in 2 different types of devices: a single-dose (1 time) prefilled autoinjector or a singledose (1 time) prefilled syringe. Your healthcare provider will prescribe the type and dose that is best for you.

• If you forget to take AIMOVIG or are not able to take the dose at the regular time, take your missed dose as soon as you remember. After that, you can continue to take AIMOVIG 1 time each month from the date of your last dose.

What are possible side effects of AIMOVIG? AIMOVIG may cause serious side effects, including:

• Allergic reactions. Allergic reactions, including rash or swelling can happen after receiving AIMOVIG. This can happen within hours to days after using AIMOVIG. Call your healthcare provider or get emergency medical help right away if you have any of the following symptoms of an allergic reaction: o swelling of the face, mouth, tongue, or throat o trouble breathing

• Constipation with serious complications. Severe constipation can happen after receiving AIMOVIG. In some cases, people have been hospitalized or needed surgery. Contact your healthcare provider if you have severe constipation.

• High blood pressure. High blood pressure or worsening of high blood pressure can happen after receiving AIMOVIG. Contact your healthcare provider if you have an increase in blood pressure.

The most common side effects of AIMOVIG include: pain, redness, or swelling at the injection site and constipation. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all of the possible side effects of AIMOVIG. Ask your pharmacist or healthcare provider for more information. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Amgen at 1-800-77-AMGEN (1-800-772-6436).

How should I store AIMOVIG?

• Store AIMOVIG in the refrigerator between 36°F to 46°F (2°C to 8°C).

• Keep AIMOVIG in the original carton. This will protect the medicine from light.

• After removing AIMOVIG from the refrigerator, it can be stored at room temperature between 68°F to 77°F (20°C to 25°C) for up to 7 days.

• Throw away AIMOVIG that has been left at room temperature for more than 7 days.

• Do not freeze.

• Do not shake.

Keep AIMOVIG and all medicines out of the reach of children.

General information about the safe and effective use of AIMOVIG.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use AIMOVIG for a condition for which it is not prescribed. Do not give AIMOVIG to other people, even if they have the same symptoms that you have. It can harm them. You can ask your pharmacist or healthcare provider for information about AIMOVIG that is written for healthcare professionals.

What are the ingredients in AIMOVIG?

• Active Ingredient: erenumab-aooe

• Inactive Ingredients: acetate, polysorbate 80, and sucrose.

The risk information provided here is not comprehensive. To learn more, talk about AIMOVIG with your healthcare provider or pharmacist. For the FDA-approved product labeling, call 1-800-77-AMGEN (1-800-772-6436) or visit www.aimovig.com.